Dynamine™ (methylliberine: 1,7,9-tetramethyluric acid) is an alkaloid isomer of Theacrine (TeaCrine®) found in kucha tea, cupuacu fruit, and some species of coffee (1)(2).
- Preliminary clinical trials demonstrate it can be combined with Theacrine (Teacrine®) for exceptional results without stimulatory effects on heart rate or blood pressure elevations (ref)*
- Anecdotal evidence has likened its effects to Theacrine (TeaCrine®) and it may enhance energy, mood, and focus. Clinical, safety, and toxicology studies are taking place currently (ref)*
Dynamine™ Capsules Mode of Action
In coffea species, the plant accumulates alkaloids and transforms them. Methylxanthines such as caffeine and theobromine are present in coffea. The metabolic reactions between methylxathines and methyluric acid produce methylliberine. First, the plant accumulates caffeine, then begins transforming theobromine to caffeine. Second, the caffeine is replaced gradually by theacrine, as theobromine and caffeine are converted to theacrine. Third, theacrine dissipates while liberine (O(2), 1,9-thrimethyluric) acid accumulates and eventually theacrine is metabolized into liberine. Fourth, the plant contains only liberine and no theacrine, and the caffeine is converted via theacrine into liberine. Methylliberine is found in low concentrations at stage 3 and 4 and is believed to be the precursor of liberine (2).
Dynamine™ is a new product and there is only one human clinical study that has already been completed and published. This study focused on combining it with the other alkaloid known as Theacrine (TeaCrine®) and found no adverse effects on heart rhythm, rate, and blood pressure, similar to the results found with Theacrine (TeaCrine®) itself. Neither are considered classically stimulatory and may provide energy and focus without unwanted cardiovascular effects usually associated with caffeine (the traditional choice of energy and focus boosters). This study used Dynamine at a dose between 100-150 mg combined with 25-50 mg TeaCrine (1).
Dynamine™ Capsules Dosage
Dynamine™ Capsules provide 100 mg of Methylliberine per 1 capsule. Suggested use for adults is 1 or 2 capsules daily, or as directed by your healthcare practitioner.
Dynamine™ Capsules Side Effects and Toxicity
Toxicology studies are currently taking place for Dynamine™. It is believed to be similar to Theacrine (TeaCrine®) in that it does not affect blood pressure and heart rate like caffeine can.
For further information, please see our References Tab above.
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
• Preliminary clinical trials demonstrate it can be combined with Theacrine (Teacrine®) Capsules for exceptional results without stimulatory effects on heart rate or blood pressure elevations*
“Proceedings of the Fifteenth International Society of Sports Nutrition (ISSN) Conference and Expo: Clearwater Beach, FL, USA. 7-9 June 2018.” Journal of the International Society of Sports Nutrition vol. 15,Suppl 1 1–37. 6 Nov. 2018, doi:10.1186/s12970-018-0256-5
• Anecdotal evidence has likened its effects to Theacrine (TeaCrine®) and it may enhance energy, mood, and focus. Clinical, safety, and toxicology studies are taking place currently*
“Dynamine™.” Compound Solutions, www.compoundsolutions.com/dynamine.html.
1. “Proceedings of the Fifteenth International Society of Sports Nutrition (ISSN) Conference and Expo: Clearwater Beach, FL, USA. 7-9 June 2018.” Journal of the International Society of Sports Nutrition vol. 15,Suppl 1 1–37. 6 Nov. 2018, doi:10.1186/s12970-018-0256-5
2. Petermann, JB, and TW Baumann. “Metabolic Relations between Methylxanthines and Methyluric Acids in Coffea L.” Plant Physiol., vol. 73, no. 4, Dec. 1983, pp. 961–4., www.ncbi.nlm.nih.gov/pubmed/?term=methylliberine.