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CDP Choline (Citicoline) Capsules


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CDP Choline, an abbreviation of cytidine-5′-diphosphocholine, referred to as Citicoline, is an essential nutrient and precursor for the neurotransmitter acetylcholine. It is an efficient source of choline that supports overall brain health, memory function, and mental energy.

CDP Choline Benefits

  • Supports cognitive function in the elderly (ref)*
  • May improve attentional performance (ref)(ref)*
  • May limit excitotoxicity from glutamate activity (ref)*
  • Promotes an increase in brain energy through improved mitochondrial functions (ref)*

CDP Choline Description

Did you know Choline is an essential nutrient?

This means most of it comes from our diets... Sadly however, most people do not get enough of it - with 90% of the US population being deficient.

Aside from enabling a whole host of bodily processes, choline is a powerhouse nutrient for brain function - improving memory, attention, energy and also being a precursor for the neurotransmitter acetylcholine.

How to increase your levels of one of the best alround brain performance nutrients?

CDP Choline is an efficient source of choline that supplies your brain with more than enough of this important nutrient.

However, there is another important reason we need optimal levels of choline in our brains - especially if we are utilising notoropics to perform at the height of our potential.

And that is optimising levels of Acetylcholine - which regulates processes such as memory, learning and attention.

Unfortunately, we cannot optimise these levels without having enough of the precursor to fuel Acetylcholine's production.

Which is precisely why an efficient source of choline is a necessity in a world where 90% of the population deficient.

By taking Pure Nootropics' CDP Choline, you are ensuring your body has enough of this critical nutrient to support optimal brain function, day in day out.

CDP Choline Dosage

Pure Nootropics’ CDP Choline Capsules provide 300 mg of Cognizin® Citicoline. Suggested use of CDP Choline capsules for adults is 1 capsule by mouth up to two times per day, or as directed by your healthcare practitioner.

No daily value has been established for Citicoline, however the RDA (Recommended Daily Allowance) of Choline ranges depending on gender and age.*

  • RDA for Choline for adult men over 18 is 550 mg/day (13)
  • RDA for Choline for adult women is 400-425 mg/day (13)


The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• Supports cognitive function in elderly*
Di Trapani, G, and M Fioravanti. “Citicoline in the Treatment of Cognitive and Behavioral Disorders in Pathologic Senile Decline.” Clin Ter, vol. 137, no. 6, 30 June 1991, pp. 403–13.,
• May improve attentional performance*
McGlade, E, et al. “The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.” J Atten Disord, vol. 23, no. 2, Jan. 2019, pp. 121–134., doi:10.1177/1087054715593633.

McGlade, E, et al. “Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.” Food and Nutrition Sciences, no. 3, June 2012, pp. 769–773., doi:10.4236/fns.2012.36103.

• May limit excitotoxicity from glutamate activity*
Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018,

• Promotes an increase in brain energy through improved mitochondrial function *
Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018,
5. Linus Pauling Institute. (2019). Choline. Web.
6. Alvarez, XA, et al. “Citicoline Improves Memory Performance in Elderly Subjects.” Methods Find Exp Clin Pharmacol, vol. 19, no. 3, Apr. 1997, pp. 201–10.,
7. Leon-Carrion, J, et al. “The Role of Citicholine {sic} in Neuropsychological Training…” NeuroRehabilitation, vol. 14, no. 1, 2000, pp. 33–40.,
8. Purves D, Augustine GJ, Fitzpatrick D, et al., editors. Neuroscience. 2nd edition. Sunderland (MA): Sinauer Associates; 2001. Glutamate. Available from:
9. Cooper GM. The Cell: A Molecular Approach. 2nd edition. Sunderland (MA): Sinauer Associates; 2000. Mitochondria. Available from:
10. Grieb, Pawel. “Neuroprotective properties of citicoline: facts, doubts and unresolved issues” CNS drugs vol. 28,3 (2014): 185-93.
11. Secades, JJ, and JL Lorenzo. “Citicoline: Pharmacological and Clinical Review, 2006 Update.” Methods Find Exp Clin Pharmacol, vol. 28, no. Suppl B, 2006, pp. 1–56.,
12. “Citicoline”. Food, Herbs, & Supplements Professional.,-herbs-supplements/professional.aspx?productid=1090#adverseEvents.
13. “Choline Fact Sheet for Health Professionals.” National Institutes of Health Office of Dietary Supplements,
14. “Uridine,”, published on 2 October 2014, last updated on 14 June 2018,
15. “What source of choline should I use?,”, published on 15 November 2013, last updated on 15 November 2013,


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CDP Choline (Citicoline) Capsules

CDP Choline (Citicoline) Capsules