Vitamin B12 is an essential vitamin, meaning it is necessary for your body to function properly. Low vitamin B12 levels have been positively associated with cognitive decline. The CDC estimates about one in 31 adults over the age of 50 are deficient in Vitamin B12.
Vitamin B12 Benefits
Supports cognitive function (ref)(ref)*
Mood support (ref)*
Promotes cognitive function and with total brain volume (ref)*
Vitamin B12 Dosage
A single dose of Pure Nootropics Sublingual Vitamin B12 contains 2500 mcg (2.5 milligrams) and should be taken once per week.
Vitamin B12 Mode of Action
B12 has several mechanisms of action in your body that are crucial to maintaining overall heath.
B12 works by maintain level of myelin in the body. Myelin is a white fatty substance that insulates nerve cells and is essential for the proper functioning of the nervous system. Damage to myelin prevents nerves from communicating effectively and impedes nervous system function.
Vitamin B12 also helps with hemoglobin synthesis, hemoglobin is a protein molecule that helps your body transport oxygen. Without B12, your body cannot produce enough hemoglobin, which can result in anemia and may further cause low energy.
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Supports cognitive function (reference) (ref)*
Agarwal, Rachna. “Vitamin B₁₂ deficiency & cognitive impairment in elderly population.” The Indian journal of medical research vol. 134,4 (2011): 410-2.
Moore E, Mander A, Ames D, Carne R, Sanders K, Watters D. Cognitive impairment and vitamin B12: a review. Int Psychogeriatr. 2012 Apr;24(4):541-56. doi: 10.1017/S1041610211002511. Epub 2012 Jan 6. PMID: 22221769.
Mood support (ref)*
Bito, Tomohiro et al. “Vitamin B12 deficiency results in severe oxidative stress, leading to memory retention impairment in Caenorhabditis elegans.” Redox biology vol. 11 (2017): 21-29. doi:10.1016/j.redox.2016.10.013
Promotes cognitive function and with total brain volume (ref)*
Tangney, C C et al. “Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination.” Neurology vol. 77,13 (2011): 1276-82. doi:10.1212/WNL.0b013e3182315a33