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Vitamin B12 Sublingual


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Vitamin B12 is an essential vitamin, meaning it is necessary for your body to function properly. Low vitamin B12 levels have been positively associated with cognitive decline. The CDC estimates about one in 31 adults over the age of 50 are deficient in Vitamin B12.


Vitamin B12 Benefits

Supports cognitive function (ref)(ref)*

Mood support (ref)*

Promotes cognitive function and with total brain volume (ref)*


Vitamin B12 Dosage

A single dose of Pure Nootropics Sublingual Vitamin B12 contains 2500 mcg (2.5 milligrams) and should be taken once per week.

Vitamin B12 Mode of Action

B12 has several mechanisms of action in your body that are crucial to maintaining overall heath.

B12 works by maintain level of myelin in the body. Myelin is a white fatty substance that insulates nerve cells and is essential for the proper functioning of the nervous system. Damage to myelin prevents nerves from communicating effectively and impedes nervous system function.

Vitamin B12 also helps with hemoglobin synthesis, hemoglobin is a protein molecule that helps your body transport oxygen. Without B12, your body cannot produce enough hemoglobin, which can result in anemia and may further cause low energy.


The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.


Supports cognitive function (reference) (ref)*

Agarwal, Rachna. “Vitamin B₁₂ deficiency & cognitive impairment in elderly population.” The Indian journal of medical research vol. 134,4 (2011): 410-2.

Moore E, Mander A, Ames D, Carne R, Sanders K, Watters D. Cognitive impairment and vitamin B12: a review. Int Psychogeriatr. 2012 Apr;24(4):541-56. doi: 10.1017/S1041610211002511. Epub 2012 Jan 6. PMID: 22221769.

Mood support (ref)*

Bito, Tomohiro et al. “Vitamin B12 deficiency results in severe oxidative stress, leading to memory retention impairment in Caenorhabditis elegans.” Redox biology vol. 11 (2017): 21-29. doi:10.1016/j.redox.2016.10.013

Promotes cognitive function and with total brain volume (ref)*

Tangney, C C et al. “Vitamin B12, cognition, and brain MRI measures: a cross-sectional examination.” Neurology vol. 77,13 (2011): 1276-82. doi:10.1212/WNL.0b013e3182315a33


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b12 sublingual supplement

Vitamin B12 Sublingual