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Choline Bitartrate (VitaCholine®) Capsules


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Choline is an essential nutrient and precursor for the neurotransmitter acetylcholine. Choline Bitartrate is a highly stable, cost-effective and bioavailable form of choline and has been branded under VitaCholine® (1)(9).

VitaCholine® Choline Bitartrate Capsules Benefits

  • Promotes healthy choline levels (ref)(ref)*
  • Supports visuomotor performance (ref)*
  • Highly bioavailable form of choline (ref)*
  • GRAS (ref)*

VitaCholine® Choline Bitartrate Capsules Mode of Action

Choline supplements can be found in many forms: choline bitartrate, choline chloride, choline citrate, citicoline (CDP), and alpha-GPC. Choline bitartrate and choline chloride are salt forms of the essential nutrient choline. All forms of choline supplements increase acetylcholine in the brain (2).

Acetylcholine is a neurotransmitter in the parts of the brain that impact memory and learning, attention, and alertness--making it one of the most beneficial neurotransmitter compounds for overall cognitive function and brain health (3).

Though choline can be found in food, less than 10% of adults in the United States are reaching the recommended daily amount (3). Common dietary sources of choline are animal-based products, dairy products, whole grains, cruciferous vegetables, nuts, and seeds (4).

Choline bitartrate is considered a simple and cost-effective form of choline but may not provide the cognitive benefits associated with other forms of choline. Instead, choline bitartrate boosts choline levels systemically (2).

Choline bitartrate is 41% choline by weight, meaning that for every 2,400 mg of choline bitartrate there is 1,000 mg of choline (2) and is a highly soluble and bioavailable form of choline. It is one of the most popular forms of choline that is found in branded foods and supplements (1), while choline chloride is still the standard for infant formulas (5).

Choline bitartrate is Generally Recognized as Safe by the U.S. FDA (6).

VitaCholine® Choline Bitartrate Capsules Dosage

Pure Nootropics’ VitaCholine® Choline Bitartrate Capsules provide 300 mg per capsule. Suggested use for adults is 1 capsule by mouth daily, or as directed by your healthcare practitioner.




VitaCholine® is a registered trademark of Balchem Corporation which is naturally sourced from only natural tartaric acid from wine production.

For further information, please see our References Tab above.


The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• Promotes healthy choline levels*
Ke, Y., et al. “Increased Brain Choline Level Observed After Choline Bitartrate Ingestion .” Proc. Intl. Sot. Mag. Reson. Med. , vol. 8, 2000, p. 1137.,
Spector, SA, et al. “Effect of Choline Supplementation on Fatigue in Trained Cyclists.” Med Sci Sports Exerc., vol. 27, no. 5, May 1995, pp. 668–73.,

• Supports visuomotor performance*
Naber, Marnix, Hommel, Bernhard, Colzato, Lorenza S. Improved human visuomotor performance and pupil constriction after choline supplementation in a placebo-controlled double-blind study. Scientific Reports. 5, 13188. 2015/08/14/online.

• Highly bioavailable form of choline*
“Choline: Essential for Every Body.” Vitacholine. Balchem Encapsulates,
“Choline Bitartrate, Choline Chloride.” SCOGS. GRAS Substances (SCOGS) Database,

1. “Choline: Essential for Every Body.” Vitacholine. Balchem Encapsulates,
2. “What source of choline should I use?”, published on 15 November 2013, last updated on 15 November 2013,
3. Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018,
4. Linus Pauling Institute. (2019). Choline. Web.
5. Cook, Sarah. “Choline: A Critical Prenatal Nutrient.” Natural Medicine Journal, 2017,
6. “Choline Bitartrate, Choline Chloride.” SCOGS. GRAS Substances (SCOGS) Database,
7. “Choline Fact Sheet for Health Professionals.” National Institutes of Health Office of Dietary Supplements,
8. “Choline.” Foods Herbs & Supplements, Professional,,-herbs-supplements/professional.aspx?productid=436.


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Choline Bitartrate (VitaCholine®) Capsules

Choline Bitartrate (VitaCholine®) Capsules