Turkey Tail Mushroom (Trametes Versicolor, also known as Coriolus Mushroom) extract is an adaptogen that promotes general well-being and may boost the immune system. It is a mushroom that has 2 forms in use today: extract of the fruiting bodies or utilized whole (including the mycelia and primordia) (1).
Pure Nootropics provides Nammex medicinal mushroom extract, using only 100% organic whole fruiting bodies which are rigorously tested and guaranteed pure.
Turkey Tail Mushroom Benefits
- Classified as an immunostimulant, it may boost the immune system (ref)(ref)*
- Promotes antioxidant activity (ref)(ref)‡*
- Supports healthy gut bacteria (ref)(ref)‡*
Turkey Tail Mushroom Mode of Action
Turkey Tail Mushroom contains naturally occurring polysaccharides. The polysaccharide peptide (PSP) and polysaccharide krestin (PSK) are the two active compounds in the mushroom. Both PSP and PSK modify biological responses and stimulate immune pathways that impact T-cell proliferation, gamma-interferon production and interleukin-2 production (2).
Research conducted with animals has suggested that the PSK in Turkey Tail Mushroom enhances glutathione peroxidase activity and contributes to its antioxidant activity (3). Medicinal mushrooms, including Turkey Tail, have been studied and their antioxidant activity is linked to their polysaccharide contents in vitro (4).
Turkey Tail’s PSP demonstrates prebiotic properties in vitro clinical studies on human gastric fluid from volunteers whose gut microbiome were compromised by the use of antibiotics (5). The polysaccharides can pass through the stomach and reach the colon unchanged and may encourage the growth of beneficial gut bacteria, specifically lactobacilli such as L. acidophilus and L. rhamnosus (6).
Turkey Tail Mushroom Dosage
Pure Nootropics’ Turkey Tail Mushroom Extract Powder provides 1000 mg per (2) level 1.0 cc scoops (provided with purchase). Suggested use is one serving by mouth daily, or as directed by your healthcare practitioner. (Due to variations in powder density, scoop measurements may fluctuate. We suggest purchasing a scale for measuring accurately. A scale allows users to better track progress and response to each dose. Scales are available for purchase through Pure Nootropics).
Turkey Tail Side Effects and Toxicity
Turkey Tail Mushroom consumed orally is well tolerated. When used orally and appropriately, it is considered likely safe. No adverse events have been reported for the Coriolus/Trametes versicolor mushroom itself; however, the isolated polysaccharide extract PSK may cause mild side effects (7). Pure Nootropics uses the extract of the whole fruiting body of the mushroom and it is a different extraction process than the individually isolated PSK extract, so side effects are rare.
Toxicity for the extract of the fruiting bodies of Coriolus/Trametes Versicolor suggests that the No Observed Adverse Effect Level (NOAEL) is 5000 mg/kg for a duration of 28 days (7).
Note: A potential and unlikely interaction with some medications that are metabolized by a specific cytochrome (CYP2C9) may occur, but the interaction is considered minor. Examples of these medications include Celebrex, Voltaren, Lescol, Glucotrol, Advil, Motrin, Avapro, Cozaar, Dilantin, Felden, Nolvadex, Tolinase, Demadex, Coumadin, and others (7). Please consult your healthcare practitioner if you are taking any medications prior to beginning supplementation with Turkey Tail. Do not use if you are pregnant or nursing.
‡ These studies are relevant and scientifically supported in-vitro studies.
For further information, please see our References Tab above.