Turkey Tail Mushroom Powder

$34.99

Pure Nootropics provides Nammex medicinal mushroom extract, using only 100% organic whole fruiting bodies which are rigorously tested and guaranteed pure.

Classified as an immunostimulant, it may boost the immune system (ref)(ref)*
Promotes antioxidant activity (ref)(ref)‡*
Supports healthy gut bacteria (ref)(ref)‡*

In stock

Product Description

Turkey Tail Mushroom (Trametes Versicolor, also known as Coriolus Mushroom) extract is an adaptogen that promotes general well-being and may boost the immune system. It is a mushroom that has 2 forms in use today: extract of the fruiting bodies or utilized whole (including the mycelia and primordia) (1).

Pure Nootropics provides Nammex medicinal mushroom extract, using only 100% organic whole fruiting bodies which are rigorously tested and guaranteed pure.

Turkey Tail Mushroom Benefits

Classified as an immunostimulant, it may boost the immune system (ref)(ref)*
Promotes antioxidant activity (ref)(ref)‡*
Supports healthy gut bacteria (ref)(ref)‡*

Turkey Tail Mushroom Mode of Action

Turkey Tail Mushroom contains naturally occurring polysaccharides. The polysaccharide peptide (PSP) and polysaccharide krestin (PSK) are the two active compounds in the mushroom. Both PSP and PSK modify biological responses and stimulate immune pathways that impact T-cell proliferation, gamma-interferon production and interleukin-2 production (2).

Research conducted with animals has suggested that the PSK in Turkey Tail Mushroom enhances glutathione peroxidase activity and contributes to its antioxidant activity (3). Medicinal mushrooms, including Turkey Tail, have been studied and their antioxidant activity is linked to their polysaccharide contents in vitro (4).

Turkey Tail’s PSP demonstrates prebiotic properties in vitro clinical studies on human gastric fluid from volunteers whose gut microbiome were compromised by the use of antibiotics (5). The polysaccharides can pass through the stomach and reach the colon unchanged and may encourage the growth of beneficial gut bacteria, specifically lactobacilli such as L. acidophilus and L. rhamnosus (6).

Turkey Tail Mushroom Dosage

Pure Nootropics’ Turkey Tail Mushroom Extract Powder provides 1000 mg per (2) level 1.0 cc scoops (provided with purchase). Suggested use is one serving by mouth daily, or as directed by your healthcare practitioner. (Due to variations in powder density, scoop measurements may fluctuate. We suggest purchasing a scale for measuring accurately. A scale allows users to better track progress and response to each dose. Scales are available for purchase through Pure Nootropics).

Turkey Tail Side Effects and Toxicity

Turkey Tail Mushroom consumed orally is well tolerated. When used orally and appropriately, it is considered likely safe. No adverse events have been reported for the Coriolus/Trametes versicolor mushroom itself; however, the isolated polysaccharide extract PSK may cause mild side effects (7). Pure Nootropics uses the extract of the whole fruiting body of the mushroom and it is a different extraction process than the individually isolated PSK extract, so side effects are rare.

Toxicity for the extract of the fruiting bodies of Coriolus/Trametes Versicolor suggests that the No Observed Adverse Effect Level (NOAEL) is 5000 mg/kg for a duration of 28 days (7).

Note: A potential and unlikely interaction with some medications that are metabolized by a specific cytochrome (CYP2C9) may occur, but the interaction is considered minor. Examples of these medications include Celebrex, Voltaren, Lescol, Glucotrol, Advil, Motrin, Avapro, Cozaar, Dilantin, Felden, Nolvadex, Tolinase, Demadex, Coumadin, and others (7). Please consult your healthcare practitioner if you are taking any medications prior to beginning supplementation with Turkey Tail. Do not use if you are pregnant or nursing.

‡ These studies are relevant and scientifically supported in-vitro studies.

For further information, please see our References Tab above.

Additional Information

Weight	0.29375 lbs
Quantity:	100g

Turkey Tail Mushroom COA

The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human conditionWe encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• Classified as an immunostimulant, it may boost the immune system (ref)(ref)*
Feng, Li, et al. “Purification and Characterization of a Novel Immunomodulatory Protein from the Medicinal Mushroom Trametes Versicolor.” Science China Life Sciences, vol. 54, no. 4, Apr. 2011, pp. 379–385., link.springer.com/article/10.1007/s11427-011-4153-2?LI=true.

“Coriolus Mushroom.” Natural Medicines Therapeutic Research. Food, Herbs & Supplements, naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=648.

• Promotes antioxidant activity (ref)(ref)*
Knežević, Aleksandar et al. “Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia” PloS one vol. 13,8 e0203064. 31 Aug. 2018, doi:10.1371/journal.pone.0203064.
Pang, ZJ, et al. “Effect of Polysaccharide Krestin on Glutathione Peroxidase Gene Expression in Mouse Peritoneal Macrophages.” Br J Biomed Sci., vol. 57, no. 2, pp. 130–6., www.ncbi.nlm.nih.gov/pubmed/10912287?dopt=Abstract.

• Supports healthy gut bacteria (ref)(ref)*
Pallav, K, et al. “Effects of Polysaccharopeptide from Trametes Versicolor and Amoxicillin on the Gut Microbiome of Healthy Volunteers: a Randomized Clinical Trial.” Gut Microbes, vol. 5, no. 4, 1 July 2014, pp. 458–67., doi:10.4161/gmic.29558.

Nowak, Renata et al. “The preliminary study of prebiotic potential of Polish wild mushroom polysaccharides: the stimulation effect on Lactobacillus strains growth” European journal of nutrition vol. 57,4 (2017): 1511-1521. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959981/.

1. “Coriolus Mushroom.” Natural Medicines Therapeutic Research. Food, Herbs & Supplements, naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=648.
2. Ng, TB. “A Review of Research on the Protein-Bound Polysaccharide (Polysaccharopeptide, PSP) from the Mushroom Coriolus Versicolor (Basidiomycetes: Polyporaceae).” Gen Pharmacol., vol. 30, no. 1, Jan. 1998, pp. 1–4., www.ncbi.nlm.nih.gov/pubmed/9457474?dopt=Abstract.
Knežević, Aleksandar et al. “Antioxidative, antifungal, cytotoxic and antineurodegenerative activity of selected Trametes species from Serbia” PloS one vol. 13,8 e0203064. 31 Aug. 2018, doi:10.1371/journal.pone.0203064.
3. Pang, ZJ, et al. “Effect of Polysaccharide Krestin on Glutathione Peroxidase Gene Expression in Mouse Peritoneal Macrophages.” Br J Biomed Sci., vol. 57, no. 2, pp. 130–6., www.ncbi.nlm.nih.gov/pubmed/10912287?dopt=Abstract.
4. Maja Kozarski, Anita Klaus, Miomir Nikšić, Miroslav M. Vrvić, Nina Todorović, Dragica Jakovljević, Leo J.L.D. Van Griensven. Antioxidative activities and chemical characterization of polysaccharide extracts from the widely used mushrooms Ganoderma applanatum, Ganoderma lucidum, Lentinus edodes and Trametes versicolor, Journal of Food Composition and Analysis, Volume 26, Issues 1–2, 2012, Pages 144-153, ISSN 0889-1575, https://doi.org/10.1016/j.jfca.2012.02.004.
5. Pallav, K, et al. “Effects of Polysaccharopeptide from Trametes Versicolor and Amoxicillin on the Gut Microbiome of Healthy Volunteers: a Randomized Clinical Trial.” Gut Microbes, vol. 5, no. 4, 1 July 2014, pp. 458–67., doi:10.4161/gmic.29558.
6. Nowak, Renata et al. “The preliminary study of prebiotic potential of Polish wild mushroom polysaccharides: the stimulation effect on Lactobacillus strains growth” European journal of nutrition vol. 57,4 (2017): 1511-1521. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959981/.
7. “Coriolus Mushroom.” Natural Medicines Therapeutic Research. Food, Herbs & Supplements, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=648#adverseEvents