Description
Benefits
Pure Nootropics Optimal Sleep Complex combines ingredients magnesium, zinc, l-tryptophan, l-theanine, valerian root and lemon balm, as well as a plus version which adds melatonin for even deeper rest.
These ingredients are commonly known to promote relaxation, stress relief and restful sleep. This natural blend provides a mild sedative effect which helps you fall asleep faster and works with your natural sleep cycle so you wake rested and refreshed.
Dosage
For both Optimal Sleep Complex and Optimal Sleep Complex Plus take one capsule before bedtime for sleep, or two capsules before bedtime for a deeper rest or as recommended by your healthcare practitioner.
Mode of Action
Melatonin is a natural hormone that plays an important role in the body’s natural sleep-wake cycle, it is produced by the pineal glad when darkness occurs and the retina sends a message to a specific part of the brain called the suprachiasmatic nucleus (SCN), which then signals the body to start producing melatonin and tells the body it is time for sleep. Using a melatonin sleep aid, such as our Optimal Sleep Complex Plus mimics this process and helps you fall asleep faster.
Magnesium works by assisting GABA receptor functioning. The role of GABA is to inhibit or reduce the activity of neurons and in turn promote relaxation and reduce anxiety. Magnesium also works as a muscle relaxant and has calming effects. It is one of the many minerals that is generally deficient in a modern diet. Additionally, there is strong evidence for zinc as a sleep aid when used in combination with magnesium, although the exact mode of action is not known.
Lemon balm works to aid sleep by inhibiting the GABA transaminase enzyme, which in turn causes mild sedation. Lemon balm is often used in combination with valerian root, as it is in our Optimal Sleep Complex, because valerian is known to stimulate Glutamate Decarboxylase, which converts Glutamate into GABA. It is thought that the combination of the two creates a two-pronged stimulation of GABA concentrations in the brain which results in a feeling of sedation and better sleep.
L-theanine crosses the blood-brain barrier and increases levels of dopamine and serotonin the brain. The mode of action includes increasing GABA activity in the brain as well.
L-tryptophan is an essential amino acid that works by playing a vital role in protein synthesis and serotonin production. Serotonin effects both sleep and mood. L-tryptophan is first converted to 5 HTP which is then converted to serotonin. Serotonin is a widely known neurotransmitter that is responsible for various functions including sleep, mood and appetite. Supplementing l-tryptophan can increase serotonin and in turn improve sleep quality.
Toxicity
The acute toxicity of melatonin as seen in both animal and human studies is extremely low. One study showed even 800 mg/kg bodyweight was not lethal.
The risks of a typically healthy person ever suffering from a magnesium overdose are very, very rare. A magnesium overdose also known as hypermagnesemia is very rare because the kidneys work to rid the body of excess magnesium, therefore overdose is most often seen in people with kidney failure.
Excessive absorption of zinc can suppress copper and iron absorption. Toxicity levels have been seen to occur after ingesting dosages greater than 225 mg.
Valerian root and lemon balm are both generally regarded as highly safe.
According to research there is no recommended maximum dosage for tryptophan.
L-theanine has a high threshold for toxicity. Headaches are the most common side effect of overdose in some individuals, however, animal studies have shown no irreversible side-effects in rats with doses of 500mg / kg of weight. For a 150 pound individual, this equates to 34,000mg of L-theanine.
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