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Optimal Choline Complex
$32.99
Pure Nootropics’ Optimal Choline Complex combines two potent choline powerhouses – CDP choline & Alpha GPC – to give you superior results. Increased choline production results in higher levels of acetylcholine in the brain for optimal cognitive performance, whilst also increasing strength outputs – talk about a double whammy!
Benefits Include
- May improve attentional performance
- Promotes increase in brain energy through increased mitochondrial function
- Supports cognitive function in the elderly
- May increase production of Human Growth Hormone
- Promotes increase in strength outputs
- May improve lower leg muscle performance
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Description
Product Description
Product Description
Pure Nootropics’ Optimal Choline Complex combines CDP Choline and Alpha GPC to achieve superior results. Both CDP Choline and Alpha GPC are essential nutrients which are precursors to acetylcholine. Acetylcholine is a neurotransmitter in the parts of the brain that impact memory and learning, attention, and alertness–making it one of the most beneficial neurotransmitter compounds for overall cognitive function and brain health.
Additionally, our Optimal Choline Complex facilitates increases in strength outputs, making it one of the best all round performance supplements you can take.
Optimal Choline Complex Properties
CDP Choline (also known as citicoline) is an essential nutrient and precursor to creating the neurotransmitter acetylcholine (1).
Alpha GPC Choline, is also a cholinergic compound found in the brain and a precursor to creating acetylcholine, functioning similarly to CDP Choline in acetylcholine synthesis.
Alpha GPC provides some additional advantages by increasing acetylcholine in the central nervous system and seems to be the more efficient choline precursor because of its bioavailability (2).
Optimal Choline Complex Dosage
Pure Nootropics’ Optimal Choline Complex capsules provide 200 mg of Citicoline and 100 mg of Alpha GPC. Suggested use of Optimal Choline Complex capsules for adults is 1 capsule by mouth up to two times per day, with or without food, or as directed by your healthcare practitioner.
Reviews (17)
17 reviews for Optimal Choline Complex
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References†
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
• Supports cognitive function in elderly and those with age related cognitive decline*
Di Trapani, G, and M Fioravanti. “Citicoline in the Treatment of Cognitive and Behavioral Disorders in Pathologic Senile Decline.” Clin Ter, vol. 137, no. 6, 30 June 1991, pp. 403–13., www.ncbi.nlm.nih.gov/pubmed/1832612.
• May improve attentional performance*
McGlade, E, et al. “The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.” J Atten Disord, vol. 23, no. 2, Jan. 2019, pp. 121–134., doi:10.1177/1087054715593633. https://www.ncbi.nlm.nih.gov/pubmed/26179181.
McGlade, E, et al. “Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.” Food and Nutrition Sciences, no. 3, June 2012, pp. 769–773., doi:10.4236/fns.2012.36103. https://cognizin.com/uploads/pdfs/improve-attention-cognizin.pdf.
• May limit excitotoxicity from glutamate activity*
Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018, www.naturalmedicinejournal.com/sites/default/files/uploads/citicoline.pdf.
• Promotes an increase in brain energy through improved mitochondrial function *
Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018, www.naturalmedicinejournal.com/sites/default/files/uploads/citicoline.pdf.
• Supports cognitive function in the elderly with age related cognitive decline more significantly
than CDP Choline*
Linder, Leah. “Alpha-GPC – An Overview.” Klaire Research and Science Healthcare Professional Article, May 2018, klaire.com/researchandscience/hcp-articles/alpha-gpc-an-overview/.
• May increase the production of the human growth hormone (HGH or somatropin) by working with
pituitary gland*
Linder, Leah. “Alpha-GPC – An Overview.” Klaire Research and Science Healthcare Professional Article, May 2018, klaire.com/researchandscience/hcp-articles/alpha-gpc-an-overview/.
• Promotes increases in strength outputs during resistance training workouts*
Ziegenfuss, Tim, et al. “Acute Supplementation with Alpha-Glycerylphosphorylcholine Augments Growth Hormone Response to, and Peak Force Production during, Resistance Exercise.” Journal of the International Society of Sports Nutrition, vol. 5, no. Suppl 1, 17 Sept. 2008, p. 15., jissn.biomedcentral.com/articles/10.1186/1550-2783-5-S1-P15.
• May enhance lower body muscle performance*
Bellar, David et al. “The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength” Journal of the International Society of Sports Nutrition vol. 12 42. 17 Nov. 2015, doi:10.1186/s12970-015-0103-x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/.
• May provide a steadier level of choline in the body than with CDP Choline *
Gatti, G, et al. “A Comparative Study of Free Plasma Choline Levels Following Intramuscular Administration of L-Alpha-Glycerylphosphorylcholine and Citicoline in Normal Volunteers.” Int J Clin Pharmacol Ther Toxicol., vol. 30, no. 9, Sept. 1992, pp. 331–5., www.ncbi.nlm.nih.gov/pubmed/1428296?dopt=Abstract.
1. Cook, Sarah. “The Unique Benefits of CITICOLINE An Emerging Nootropic and Brain-Health Nutrient.” Natural Medicine Journal, 2018, www.naturalmedicinejournal.com/sites/default/files/uploads/citicoline.pdf.
2. Linder, Leah. “Alpha-GPC – An Overview.” Klaire Research and Science Healthcare Professional Article, May 2018, klaire.com/researchandscience/hcp-articles/alpha-gpc-an-overview/.
3. McGlade, E, et al. “The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.” J Atten Disord, vol. 23, no. 2, Jan. 2019, pp. 121–134., doi:10.1177/1087054715593633. https://www.ncbi.nlm.nih.gov/pubmed/26179181.
McGlade, E, et al. “Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women.” Food and Nutrition Sciences, no. 3, June 2012, pp. 769–773., doi:10.4236/fns.2012.36103. https://cognizin.com/uploads/pdfs/improve-attention-cognizin.pdf.
4. Ziegenfuss, Tim, et al. “Acute Supplementation with Alpha-Glycerylphosphorylcholine Augments Growth Hormone Response to, and Peak Force Production during, Resistance Exercise.” Journal of the International Society of Sports Nutrition, vol. 5, no. Suppl 1, 17 Sept. 2008, p. 15., jissn.biomedcentral.com/articles/10.1186/1550-2783-5-S1-P15.
5. Bellar, David et al. “The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength” Journal of the International Society of Sports Nutrition vol. 12 42. 17 Nov. 2015, doi:10.1186/s12970-015-0103-x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650143/.
6. Gatti, G, et al. “A Comparative Study of Free Plasma Choline Levels Following Intramuscular Administration of L-Alpha-Glycerylphosphorylcholine and Citicoline in Normal Volunteers.” Int J Clin Pharmacol Ther Toxicol., vol. 30, no. 9, Sept. 1992, pp. 331–5., www.ncbi.nlm.nih.gov/pubmed/1428296?dopt=Abstract.
7. Secades, JJ, and JL Lorenzo. “Citicoline: Pharmacological and Clinical Review, 2006 Update.” Methods Find Exp Clin Pharmacol, vol. 28, no. Suppl B, 2006, pp. 1–56., www.ncbi.nlm.nih.gov/pubmed/17171187.
8. Grieb, Pawel. “Neuroprotective properties of citicoline: facts, doubts and unresolved issues” CNS drugs vol. 28,3 (2014): 185-93. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933742/.
9. Barbagallo Sangiorgi, G, et al. “Alpha-Glycerophosphocholine in the Mental Recovery of Cerebral Ischemic Attacks. An Italian Multicenter Clinical Trial.” Ann N Y Acad Sci., vol. 717, 30 June 1994, pp. 253–69., www.ncbi.nlm.nih.gov/pubmed/8030842?dopt=Abstract.
10. “Alpha-GPC.” Food, Herbs & Supplements, Professional, naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=1087#safety.
11. “Choline Fact Sheet for Health Professionals.” National Institutes of Health Office of Dietary Supplements, ods.od.nih.gov/factsheets/Choline-HealthProfessional/#h2.
12. Brownawell, AM, et al. “Safety Assessment of AGPC as a Food Ingredient.” Food Chem Toxicol., vol. 49, no. 6, June 2011, pp. 1303–15., doi: 10.1016/j.fct.2011.03.012.
13. “Citicoline.” Foods Herbs & Supplements, Professional, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=1090#adverseEvents.
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Ross (verified owner) –
Without a doubt, boosting acetylcholine levels is the first step when beginning a nootropics stack or regimen. This is a great product and I highly recommend seeing the benefits it can provide for yourself. This being a blend of two of the more/most bioavailable forms, this is a good choline supplement to start on.
I would like to see more options on blend ratios, but offering both in one supplement is a highly effective format.
Christopher (verified owner) –
Pure Nootropics’ Optimal Choline Complex is a product I’ve been searching for for quite some time at various nootropic retail Websites. It’ priced well for the highly effecttlve balance of Choline types supplied nicely in a bottle of (green) capsules. Again, amazing product and works extremely well, and synergistically when taken with the racetams. Another top rate product from Pure Nootropics. This type of choli e, as opposed to Choline Bitartrate, especially is great. I’ve just ordered more, in fact, for the fourth time in a row.
Tom Twist –
It is amazing how it works.. Its awesome.
Myles (verified owner) –
I had started getting headaches after using the various racetam supplements (Py/Oxi/phenyl). My prefered use of the racetam’s is just taking one in the morning before a large day of studying with a good nights sleep. As far as this product is concerned, I’ve found that a 1:2 racetam to choline ratio has abolished my headaches. To my knowledge its well priced and I believe is a must buy if you are considering using racetam’s long term.
Jacob G. (verified owner) –
With this supplement, my brain got much sharper, recalling distant and recent details I had long fuzzied.
Amber H. (verified owner) –
Great for focus and ADD
Denise G. (verified owner) –
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Richard G. (verified owner) –
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Sho V. (verified owner) –
Imagine having CDP Choline and Alpha GPC both in one. Take it and combine it with any type of other stacks and you have your daily doses of Choline. Best combination is to combine it with Modalert.
Jeffrey A. (verified owner) –
Excellent product
billy s. (verified owner) –
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Harold W. (verified owner) –
I have been using Optimal Choline Complex for a few months now, very, pleased with your products.I’m here because of Mansal Denton.Thank You.
J (verified owner) –
Excellent. Just wish you would get more in stick. Waiting patiently.
M. Williams (verified owner) –
Some mornings I neglect to reach for my Op.Choline Complex – within the hour I notice my usual sharp clarity diminishing – oh, oh. Optimal Choline Complex is quite the fix for increased clarity!
James –
Good stuff, works really well for me.
William Adams –
good supplement. good service.
daniel brawner (verified owner) –
I bought this along with the Fasoracetam, so I’ll be copy/pasting the review since I’ve been using them together since it wouldn’t make sense to leave a different review.
Anyways, I’ve been really enjoying the focus, I am usually a scatter brain and it’s hard for me to focus on my writing and reading and this has been incredible for keeping me focused. I’ve not been using it for too long, so it may be in-part placebo affect, but after about 15mins to an hour after consumption, I notice a really strong sense of clarity and focus, and I feel great.