Name: Aniracetam Capsules &amp; Powder
SKU: 2597
Availability: InStock
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Product Description

thirdpartysafety

Aniracetam Capsules

Aniracetam is a nootropic compound in the racetams group.

Aniracetam (1-P-Anisoyl-2-Pyrrolidinone) is an organic compound in the class of benzoic acids and derivatives. It interacts between the serotonergic, dopaminergic and cholinergic systems (ref)*
Synthesized to be fat soluble (ref)*: Fat-soluble compounds can access the brain via the blood-brain-barrier (ref)*
Assured Purity: Rigorously tested for quality & purity by third-party Certificate of Analysis*

Aniracetam Chemical Properties

Aniracetam is an AMPAkine which means it modulates the AMPA receptors in the hippocampus (the part of the brain associated with learning and memory) by providing quick, excitatory transmission between synapses. AMPA receptors interact with the glutamate neurotransmitters in the brain and lengthen the amount of time the synaptic channel is open between communicating neurons. The ability of the glutamate neurotransmitters to transmit and communicate between the synapses of neurons is then enhanced. This long-term potentiation of synaptic communication is a helpful mechanism for enhanced learning and memory (5)*.

Aniracetam’s molecular formula is C₁₂H₁₃NO₃and it has a molecular mass of 219.24 g/mol.

Aniracetam is also known as 1-P-Anisoyl-2-Pyrrolidinone and the CAS Number is 72432-10-1 (1).

The general systemic bioavailability is 0.2% (3).

The elimination half-life is 35 minutes (2) and the biological half-life is 1-2.5 hours (1).

Aniracetam Capsules

Pure Nootropics offers Aniracetam in 750 mg capsules in both 30 and 60 count bottles.

Bulk powder is available in 75 gram and 200 gram quantities.

Aniracetam Toxicity

In preclinical safety data, Aniracetam was very well tolerated in the animal model consisting of mice, rats, rabbits, and dogs. Both single and consecutive doses were administered. At extremely high doses, the side effects were found to generally minor (6). A lethal dose in rats was 4.5 g/kg and 5 g/kg in mice, which works out to be approximately 500 or more times the standard dose of the 1.5 g dose a human would normally consume. Therefore, it is extremely hard to achieve toxicity with Aniracetam (4).

For further information, please see our References Tab above.

Additional Information

Weight	0.10625 lbs
Dimensions	1.95 × 1.95 × 3.95 in
Quantity	75g (powder only), 200g (powder only), Capsules (30 x 750mg), Capsules (60 x 750mg)

ANIRACETAM CERTIFICATES OF ANALYSIS 08/2018

ANIRACETAM CERTIFICATES OF ANALYSIS 06/2018

The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. This product is sold as a research chemical and is for research purposes only; we recommend consulting a professional about how to handle this chemical. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• Aniracetam (1-P-Anisoyl-2-Pyrrolidinone) is an organic compound in the class of benzoic acids and derivatives (ref). It interacts between the serotonergic, dopaminergic and cholinergic systems (ref)*

“Aniracetam.” Drug Bank, www.drugbank.ca/drugs/DB04599.

“Aniracetam.” PubChem Open Chemistry Database, https://pubchem.ncbi.nlm.nih.gov/compound/2196#section=Pharmacology-and-Biochemistry.

• Synthesized to be fat soluble (ref): Fat-soluble compounds can access the brain via the blood-brain-barrier (ref)*

“Aniracetam,” Examine.com, published on 29 June 2014, last updated on 14 June 2018, https://examine.com/supplements/aniracetam/.

Ronald E. Baynes, Kelly J. Dix, Jim E. Riviere, Chapter 6 – Distribution and Pharmacokinetics Models**This chapter was editorially abbreviated and reformatted from K.J. Dix, 2001, Absorption, distribution and pharmacokinetics, Chapter 24 in Handbook of Pesticide Toxicology (R. Krieger, Ed.), 2nd edition, Academic Press, San Diego., Editor(s): Ernest Hodgson,dPesticide Biotransformation and Disposition, Academic Press,2012,Pages 117-147,ISBN 9780123854810, https://doi.org/10.1016/B978-0-12-385481-0.00006-X.

1. “Aniracetam.” PubChem Open Chemistry Database,
https://pubchem.ncbi.nlm.nih.gov/compound/2196#section=Pharmacology-and-Biochemistry.

2. “Aniracetam,” Examine.com, published on 29 June 2014, last updated on 14 June 2018, https://examine.com/supplements/aniracetam/.

3. Schlappi, Bernhard, et al. “Aniracetam: Toxicological Profile of a Chemical Derivative of 2-Pyrrolidinone.” Drug Investigation, vol. 5, no. 1, June 1993, pp. 50–67., http://link.springer.com/article/10.1007/BF03258427.

4. Wijayawardhane, Nayana. THERAPEUTIC EFFECTS OF ANIRACETAM ON COGNITIVE DEFICITS INDUCED BY ETHANOL TERATOGENICITY: A NOVEL TREATMENT APPROACH THROUGH SYNAPTIC AMPA RECEPTOR MODULATION. Auburn University Dissertation. May 10, 2007. https://etd.auburn.edu/xmlui/bitstream/handle/10415/822/WIJAYAWARDHANE_NAYANAKANTHI_21.pdf?sequence=1&isAllowed=y.

5. Gumru, Salih, and Feyza Aricoglu. “Ampakines: Selective AMPA Receptor Modulators with Potential Benefits.” Marmara University, School of Pharmacy Department of Pharmacology and Psychopharmacology Research Unit, Istanbul, Turkey, 21 Nov. 2012, pdfs.semanticscholar.org/ffad/a3b5abaf45e96723846d0e8424e822ecdd19.pdf.

6. Schlappi, Bernhard, et al. “Aniracetam: Toxicological Profile of a Chemical Derivative of 2-Pyrrolidinone.” Drug Investigation, vol. 5, no. 1, June 1993, pp. 50–67., link.springer.com/article/10.1007/BF03258427.