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1-2-Go
$17.99 $14.99
The benefits of Caffeine + L-theanine are now formulated in our 1-2-GO product to provide all the nootropic benefits of Caffeine, L-theanine and Theobromine.
Caffeine + L-Theanine Combination Benefits
- May improve cognitive performance (ref)*
- Promotes benefits of caffeine without unwanted effects (ref)*
- Supports focus and attention (ref)*
- Promotes wakefulness and alertness (ref)*
- L-Theanine is General Recognized As Safe (GRAS) by U.S. FDA (ref)
Theobromine Benefits
- A naturally occurring, mild stimulant responsible for the mood enhancing effects of chocolate (ref)*
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Product Description
The benefits of Caffeine + L-theanine are now formulated in our 1-2-GO product to provide all the nootropic benefits of Caffeine, L-theanine and Theobromine.
Caffeine + L-Theanine Combination Benefits
- May improve cognitive performance (ref)*
- Promotes benefits of caffeine without unwanted effects (ref)*
- Supports focus and attention (ref)*
- Promotes wakefulness and alertness (ref)*
- L-Theanine is General Recognized As Safe (GRAS) by U.S. FDA (ref)
Theobromine Benefits
- A naturally occurring, mild stimulant responsible for the mood enhancing effects of chocolate (ref)*
1-2-GO Benefits
Caffeine and Theobromine are found naturally combined in cocoa, cacao, and chocolate. Caffeine, Theobromine and L-Theanine can all be found in some teas (1).
- Caffeine + L-Theanine Combination
By combining L-theanine with caffeine, some of the undesirable side of effects of caffeine use is lessened. L-Theanine reduces caffeine’s stimulatory effects without modifying the other mechanisms for focus that caffeine offers. L-Theanine interacts with caffeine by “taking the edge off” and still allows the alertness provided by caffeine to remain (2).
The combination of L-theanine with caffeine also may improve cognitive function (3), may eliminate the blood vessel constriction normally experienced with caffeine (4), and help keep the mind from experiencing wandering, or distraction (5).
The cognitive benefits associated with caffeine in combination with L-Theanine were studied on 50 mg caffeine to 100 mg L-Theanine, so we recommend caffeine to L-Theanine ratio should be 1-part caffeine to 2 parts L-Theanine (6).
- Theobromine
Theobromine is a mood-enhancing compound naturally present in chocolate. Theobromine is a mild stimulant that interacts with the dopamine pathways in the brain (7). Theobromine and caffeine are both methylxanthines that stimulate the central nervous system through blocking adenosine receptors (8). In comparison to caffeine, Theobromine is a much weaker stimulant and only exerts about one-tenth of the effects of other methylxanthines (Review Article Health Benefits of Dark Chocolate).
The combination of caffeine and theobromine in chocolate, cocoa, and cacao is linked to the pleasurable effects and appeal of chocolate. Theobromine has also shown promise in promoting blood vessel health (9).
1-2-GO Dosage
Pure Nootropics’ 1-2-GO provides 390 mg of a proprietary blend of L-Theanine, Theobromine, and Caffeine per 1 capsule. Suggested use for adults is 1 capsule by mouth not more than every 4-6 hours, not to exceed more than 4 capsules in 24 hours.
1-2-GO Side Effects
- L-Theanine Side Effects
L-Theanine, regardless of chemical synthesis, biosynthesis, or naturally occurring, is General Recognized As Safe (GRAS) by U.S. FDA.
L-Theanine is very well tolerated and side effects may include headaches and increased sleepiness (10).
Animal research indicates that the No Observed Adverse Effect Level of L-theanine is greater than
4000 mg/kg in rats (10).
(Note: Due to L-Theanine’s effects on reducing blood pressure, possible interactions with pharmaceutical blood pressure medications and herbs/supplements that may occur.)
- Caffeine Side Effects
In moderate doses, caffeine is usually well tolerated in adults and children. Side effects may include insomnia, restlessness, nervousness, nausea, vomiting, gastric irritation, tachycardia, tremors, quickened respiration, convulsions, headache, agitation, anxiety, chest pain, and irregular heartbeat. Large doses of caffeine may cause tachycardia, metabolic acidosis, ketosis, and hyperglycemia. Children and the elderly may experience more adverse effects from caffeine. Chronic use of large amounts of caffeine may cause tolerance, psychological dependence, and abrupt stopping of caffeine use may cause physical withdrawal symptoms (11).
The lethal dose of caffeine in adults is approximately 10-14 grams per kilogram but fatality has also occurred at lower doses (11).
Caffeine has many pharmaceutical medication and herb interactions. If you are taking any medications, herbs, or supplements, please consult your healthcare practitioner before beginning a supplementation with caffeine.
- Theobromine Side Effects
Theobromine is toxic to many animals, but in normal consumption it is safe for humans. A standard 40 g dark chocolate bar contains about 250 mg of Theobromine (9). Chocolates with higher cocoa/cacao content have more theobromine than milk chocolate.
Higher doses of 50-100 g of cocoa caused sweating, severe headaches, and trembling (12).
Theobromine is very toxic to dogs because they metabolize it so slowly and they can experience theobromine poisoning (13). Please keep 1-2-GO out of the reach of curious pets.
For further information, please see our References Tab above.
Additional Information
| Weight | 0.11875 lbs |
|---|---|
| Dimensions | 1.95 × 1.95 × 3.95 in |
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The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
• May improve cognitive performance
Owen, GN, et al. “The Combined Effects of L-Theanine and Caffeine on Cognitive Performance and Mood.” Nutr Neurosci., vol. 11, no. 4, Aug. 2008, pp. 193–8., doi: doi:10.1179/147683008X301513.
• Promotes benefits of caffeine without unwanted effects
Dodd, FL, et al. “A Double-Blind, Placebo-Controlled Study Evaluating the Effects of Caffeine and L-Theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood.” Pyschopharmacology (Berl), vol. 232, no. 14, July 2015, pp. 2563–76., doi:10.1007/s00213-015-3895-0.
• Supports focus and attention
Kahathuduwa, CN, et al. “l-Theanine and Caffeine Improve Target-Specific Attention to Visual Stimuli by Decreasing Mind Wandering: a Human Functional Magnetic Resonance Imaging Study.” Nutr Res., vol. 49, Jan. 2018, pp. 67–78., doi:10.1016/j.nutres.2017.11.002.
• Promotes wakefulness and alertness
Giesbrecht, T, et al. “The Combination of L-Theanine and Caffeine Improves Cognitive Performance and Increases Subjective Alertness.” Nut, vol. 13, no. 6, Dec. 2010, pp. 283–90., doi:10.1179/147683010X12611460764840.
• General Recognized as Safe (GRAS) by U.S. FDA
“GRAS Notices.” U.S. Food & Drug Administration, www.accessdata.fda.gov/scripts/fdcc/index.cfm?set=GrASNotices&sort=Date_of_closure&order=ASC&showAll=true&type=basic&search=theanine.
Theobromine Benefits
• A naturally occurring, mild stimulant responsible for the mood enhancing effects of chocolate
Baggott, Matthew J et al. “Psychopharmacology of theobromine in healthy volunteers.” Psychopharmacology vol. 228,1 (2013): 109-18. doi:10.1007/s00213-013-3021-0.
1. IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. Coffee, Tea, Mate, Methylxanthines and Methylglyoxal. Lyon (FR): International Agency for Research on Cancer; 1991. (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 51.) Theobromine. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507032/.
2. “Caffeine”. Examine.com, published on Jul 26 2014, Last updated Mar 29, 2019. https://examine.com/supplements/caffeine/.
3. Giesbrecht, T, et al. “The Combination of L-Theanine and Caffeine Improves Cognitive Performance and Increases Subjective Alertness.” Nut, vol. 13, no. 6, Dec. 2010, pp. 283–90., doi:10.1179/147683010X12611460764840.
4. Dodd, FL, et al. “A Double-Blind, Placebo-Controlled Study Evaluating the Effects of Caffeine and L-Theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood.” Pyschopharmacology (Berl), vol. 232, no. 14, July 2015, pp. 2563–76., doi:10.1007/s00213-015-3895-0.
5. Kahathuduwa, CN, et al. “l-Theanine and Caffeine Improve Target-Specific Attention to Visual Stimuli by Decreasing Mind Wandering: a Human Functional Magnetic Resonance Imaging Study.” Nutr Res., vol. 49, Jan. 2018, pp. 67–78., doi:10.1016/j.nutres.2017.11.002.
6. Owen, GN, et al. “The Combined Effects of L-Theanine and Caffeine on Cognitive Performance and Mood.” Nutr Neurosci., vol. 11, no. 4, Aug. 2008, pp. 193–8., doi:doi: 10.1179/147683008X301513.
7. “Where do cravings come from?” Examine.com, published Apr 17, 2017, Last updated Apr 18, 2017. https://examine.com/nutrition/where-do-cravings-come-from/.
8. Franco, R, et al. “Health Benefits of Methylxanthines in Cacao and Chocolate.” Nutrients., vol. 5, no. 10, 18 Oct. 2018, pp. 4159–73., doi:10.3390/nu5104159.
9. Baggott, Matthew J., et al. “Psychopharmacology of Theobromine in Healthy Volunteers.” Psychopharmacology, 31 Jan. 2013, doi:10.1007/s00213-013-3021-0.
10. “Theanine.” Food, Herbs & Supplements, Professional. Natural Medicines, Therapeutic Research, naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=1053.
11. “Caffeine.” Food, Herbs & Supplements, Professional. Natural Medicines, Therapeutic Research, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=979#toxicology.
12. “3,7-Dimethylxanthine (Theobromine)”. Toxnet, US National Library of Medicine. 1 December 2017. Retrieved 13 November 2018.
13. “Theobromine.” Wikipedia, en.wikipedia.org/wiki/Theobromine#cite_ref-33.
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Roshan (verified owner) –
Great product. Works like 5hr Energy without any jitters. After my 9-5 work day i take one pill when i reach home and i can stay up late and get good amount of studying done without any crash.
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George (verified owner) –
I love 1-2-Go, it gives me the energy I need in the morning with no crash, jitters, or noticeable after effects. I also use the 1-2-Go to replace energy drinks and 5-hour energy as I tend to get roughly the same results from both, I like the 1-2-Go better because lots of energy drinks are full of sugar and 5 hour energy has a very medicine like taste.
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Adolfo –
Honestly, I feel I have the upper hand while dosing on this product, helps me consentrate with creativity and hold arguments down with advance vocabulary fluidity! Thank you
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Noah (verified owner) –
Definitely works, it helped those whom I shared it with to stay smoothly energized in the afternoon when the days over with work still needed to be done. Personally I’m too caffeine sensitive too notice any effects from the L-Theanine.
But it did help others.
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Kas (verified owner) –
This gives me a stable focus for several hours, similar to several cups of black tea. I work night shift and this helps me stay focused after lunch.
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williams19elizabeth (verified owner) –
Absolutely incredible. This has changed my survival vs bronchospasms, anxiety
States that go beyond the typical symptoms of anxiety attacks not yet well understood. It also lets
Me feel relaxed and unstressed so I am
Able to focus or sleep. I get to choose. No more crashing. Simultaneous fix to both sleep schedule and airway closure. Wish it came in a larger bulk quantity.
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Prema –
I’d like to know how much of each component are in this product.
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Admin Eric Balaster –
Hello, our 1-2-Go Contains the following:
160 mg – L-theanine
150 mg – Theobromine
80 mg – Caffeine
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James D. (verified owner) –
“Nice lift.”
Takes about 45 minutes to kick in but it definitely helps when I am feeling sluggish and need a lift. I also stack it with noopept for an even bigger lift.
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Timothy J. (verified owner) –
01-02-& WHAOOOO!
Before I found Pure Nootropics and 1,2, GO had been taking prescription stimulants for focus and that came with all the negative side effects. I then started looking for natural alternatives with no luck. Somehow I stumbled upon Pure Nootropics and after researching the site I found 1,2, GO. At first, I was a little skeptical however once I received my first bottle which was last year. I was an instant believer. I really felt a jolt of controlled energy and focus. It was exactly what I was looking for all of the benefits with none of the side effects. I have been taking it ever since. Overall if your looking for a substitute to Adderall or any other doctor prescribed stimulant for focus and energy, I would highly recommend 1,2, GO. I have even started to stack it with other nootropics such as sulbutiamine, noopept, etc and receiving some really good results.
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Jeffrey M. (verified owner) –
Just the boost I was looking for. It doesn’t give you the jitters. Just pure alertness and total focused concentration. I love 1-2 GO from Pure Nootropics. It’s clean and pure and in just the right amount for me.
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Wayne D. (verified owner) –
The product I ordered, “01-02 Go,” helps to remain focused and alert. I highly recommend this product!!
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sanchezrecardo5 (verified owner) –
I’d like to know is the number on the bottom of the bottle the expired date? For I received one with the year 2018 on it
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CassandraRomero –
Hello there, thanks for reaching out! This is actually the batch number which actually indicates the manufacture date, that means this particular bottle was made in 2018. Please let us know if you have any additional questions or concerns.
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