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PRODUCT INFORMATION

Centrophenoxine is a compound which is a derivative of Dimethylaminoethanol (DMAE) and pCA (para-chlorophenoxyacetic acid) (1). 

    Centrophenoxine Properties

    Centrophenoxine is an ester (or derivative) of DMAE (Dimethylaminoethanol) that has been modified with the addition of pCA (para-chlorophenoxyacetic acid) (1).

     

    Pure Nootropics’ Centrophenoxine provides 250 mg per 1 capsule. 

    DO NOT HANDLE if pregnant. Like DMAE, Centrophenoxine can produce birth defects (8).  AVOID HANDLING if you have high blood pressure.

     

    For further information, please see our References Tab above.

    Reference

    The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

     

    1. National Center for Biotechnology Information. PubChem Database. Centrophenoxine, CID=23615812, https://pubchem.ncbi.nlm.nih.gov/compound/23615812 (accessed on Mar. 22, 2019)
    2. Georgiev, VP, et al. “Participation of Adrenergic Mechanisms in Brain Acetylcholine Release Produced by Centrophenoxine.” Acta Phsyiol Pharmacol Bulg., vol. 5, no. 4, 1979, pp. 21–6., www.ncbi.nlm.nih.gov/pubmed/120676.
    3. Roy, D, et al. “Effect of Centrophenoxine on the Antioxidative Enzymes in Various Regions of the Aging Rat Brain.” Exp Gerontol., vol. 18, no. 3, 1983, pp. 185–97., www.ncbi.nlm.nih.gov/pubmed/6416880.
    4. Cho, Sohee, and Eun Seong Hwang. Recent Advances in Cytometry, Part B, vol. 103, 2011, pp. 149–188., www.sciencedirect.com/science/article/pii/B9780123854933000073.
    5. Zs-Nagy, I, and I Semsei. “Centrophenoxine Increases the Rates of Total and MRNA Synthesis in the Brain Cortex of Old Rats: an Explanation of Its Action in Terms of the Membrane Hypothesis of Aging.” Exp Gerontol., vol. 19, no. 3, 1984, pp. 171–8., www.ncbi.nlm.nih.gov/pubmed/6207041.
    6. Pek G, Fulop T, Zs-Nagy I (1989) Gerontopsychological studies using NAI (‘Nurnberger Alters-Inventar’) on patients with organic psychosyndrome (DSM III, Category 1) treated with centrophenoxine in a double blind, comparative, randomized clinical trial. Arch Gerontol Geriatr 9, 17-30
    7. Popa R, Schneider F, Mihalas G et al. (1994) Antagonic-stress superiority versus meclofenoxate in gerontopsychiatry type dementia)… Arch Gerontol Geriatr 19 Suppl 1, 197-206.
    8. “Centrophenoxine” Examine.com, published on 2 July 2013, last updated on 14 June 2018, https://examine.com/supplements/centrophenoxine/#ref4.
    9. “Centrophenoxine.” www.alzdiscovery.org/cognitive-vitality/ratings/centrophenoxine.

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    Centrophenoxine Capsules

    Centrophenoxine Capsules

    $16.99
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