Smart PS™ Softgels

$29.99 $26.99

Soft Gel Technologies, Smart PS™ soft gels feature an exclusive phosphatidylserine material that has significantly increased stability for enhanced memory, attention and athletic performance.

  • Decreases the loss of brain cells (ref)
  • Helps slow down age-related cognitive decline, including memory, attention and concentration (ref)
  • Improves anxiety and depression in the elderly (ref)
  • Reduces the risk of cognitive dysfunction, including Alzheimer’s disease (ref)
  • Enhances athletic performance and recovery (ref)

60 x 100mg softgels (60 servings)

In stock



Smart PS™ (Phosphatidylserine) works to boost memory and overall cognition. This also includes greater learning capacity and improved memory recall. Research also indicates that Smart PS supplementation increases mental stamina along with improved focus and concentration. The benefits of this supplement are considered to be long-term and it may even slow down the aging process on your brain.


Dosage for Phosphatidylserine is  100mg, taken up to 3 times a day to total 300mg daily. Total daily dosage should not exceed 600 mg.

Mode of Action

Phosphatidylserine is a phospholipid that is highly present in neural tissue.  It is responsible for widespread functions in the body. It is a crucial building block of cell membranes, ensuring their fluidity and structure, and ultimately, their function.  Why is that significant? Research shows that the cell membrane is much more important than previously thought. Rather than simply being a container for the contents of the cell, the cell membrane is the master controller of signal transmission. It is the molecular mechanism that tells the cell what to do in response to the environment. In essence, the cell membrane — not the nucleus — is the brain of the cell. And it relies on sufficient supplies of PS to function.


Smart PS™ has a relatively high toxicity level according to all available research.

Additional information

Weight .15 lbs
Dimensions 1.95 x 1.95 x 3.95 in

Full Analysis

Phosphatidylserine (PS) is a phospholipid that is a major component of cell membranes, making it a highly valuable nutrient for enhancing cognitive function.

  • Shown improvements in memory and learning processes (reference)
  • Significantly reduce symptoms of cognitive decline in persons with Alzheimer’s disease (ref)
  • Improved exercise capacity in men. Considerable Ergogenic properties (ref)
  • Faster recovery in athletes, possible decrease in muscle soreness and improved well-being (ref)
  • ADHD (ref)
  • Increased cognitive performance in those with declining cognition (ref)

Smart PS™ Benefits

Smart PS™ has a variety of positive benefits, both cognitive and physical. Research has shown it can protect the integrity of brain cells that are important to learning and memory. Additionally, it can help slow age-related cognitive decline. It can preserve memory, attention, word recall and concentration. When elderly adults supplement 300mg of PS daily, it is shown to have profound memory improvement after 12-weeks of use.

Smart PS™ also supports mood and has been researched as a treatment for depression and depressive symptoms in the elderly. Two studies in elderly women suffering from either major depression or depressive symptoms found that PS significantly reduced symptoms of anxiety and depression and significantly improved feelings of occasional stress and low mood.

Smart PS™ Studies and Side Effects

Smart PS and its positive effects are backed by a good amount of research, most of which centers around cognitive abilities and further prevention of cognitive decline. Perhaps most impressively, research has indicated that soy-derived PS may “turn back” the aging process. When elderly adults supplemented with 300mg of soy-PS per day.

Additional research regarding physical abilities, specifically endurance and exercise capacity are also promising. A recent study on healthy male subjects found that PS was effective at combating exercise-induced stress and physiological degradation from over-exercise by blunting increases in cortisol levels. Other research has shown PS improves athletic performance and exercise capacity, while decreasing muscle soreness.

Soft Gel Technologies’ Smart PS™ material is Generally Recognized as Safe (GRAS). A safety study in elderly human subjects showed that a dosage of 200mg, three times per day, caused no significant changes in biochemical or hematological safety parameters, and did not affect blood pressure or heart rate. Additionally, PS has no known side effects, and unlike other remedies, does not influence neurotransmitters such as serotonin.

Buy Phosphatidylserine

You can purchase Phosphatidylserine in local stores and many sites online. Unfortunately, PS is highly unstable and therefore prone to degradation. In fact, a recent shelf-life study, performed on a standard fluid PS material by an independent international laboratory for phospholipid analysis, showed dismaying results. Within 12 weeks of encapsulation, the standard fluid PS material had degraded by 10%. Within 18 weeks, it had degraded by nearly 20%.

Pure Nootropics does have a reputation for high quality products, however, and our Smart PS™ is specifically formulated to overcome the issue of PS stability.

Soft Gel Technologies Smart PS™ was created with an exclusive fluid dispersion PS material, that has enviable stability. Shelf-life studies on Smart PS™, performed by the same independent laboratory mentioned above, found that even after 24 months, the material showed absolutely no degradation. It was as potent at month 24 as it was the day it was encapsulated.


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