Produced by worker bees, Royal Jelly is a nutritious jelly also known as a superfood due to the protein, carbohydrates, fatty acids, free amino acids, sugars, minerals, and vitamins (1, 2).
Royal Jelly Benefits
- Promotes glucose tolerance (ref)*
- Mood support (ref)*
- Promotes red blood cell production (ref)*
- Supports male sexual health (ref)*
Royal Jelly is emerging as a subject of interest in the medical community, but thus far, there have not been many studies conducted with humans.
The following are examples of dynamics associated with Royal Jelly through the animal model and may not be representative of the effects in the human body:
- Supports cognitive function (in mice) (ref)*
Royal Jelly Mode of Action
Royal Jelly is a secretion from the salivary glands (hypopharyngeal and mandibular glands) of the worker honey bees which is used as the queen bee’s food (2). Queen bees ingest royal jelly for the duration of their lives, unlike the other adult bees. Royal jelly is often fed to the queen larvae and young larvae of the other bees (1).
Royal Jelly consists of several nutrients which include lipids (80-85% of the total content is fatty acids), dietary fatty acids (such as 10-HDA which is unique to royal jelly and consists of 32% of content), peptides, 57-kDa protein (unique to queen bees), carbohydrates (at 10-16% volume by weight), mineral salts, acetylcholine, Adenosine Triphosphate (ATP), and testosterone (1).
A lyophilized (freeze-dried) concentrate increases the bioavailability of royal jelly for humans. Due to the varying composition of royal jelly due to season and cultivation, the macronutrient composition of royal jelly varies (1).
The areas in which Royal Jelly has been studied in humans have the greatest promise is in glucose metabolism, both in humans and in vitro (3, 4). The information on Royal Jelly supplementation in humans is scarce. Several animal studies have shown some promise in the areas of longevity but the studies were conducted on nematodes (worms) which may not be representative as to the effects in the human body (5).
Royal Jelly Dosage
Pure Nootropics’ Royal Jelly provides 500 mg of 6-10% HDA freeze-dried concentrate which is equivalent to 1500 mg of fresh Royal Jelly per 1 capsule. Suggested use for adults is 1 capsule daily, or as directed by your healthcare practitioner.
Royal Jelly Side Effects and Toxicity
Royal Jelly can cause allergic reactions in individuals with a history of asthma or atopy (2). Allergic reactions can also occur in those with a severe pollen allergy (1). In severe cases of allergic reactions, anaphylaxis, asthmaticus, and death may occur. Allergic and IgE-mediated hypersensitive individuals should avoid the use of Royal Jelly (2).
In non-allergic individuals, Royal Jelly appears well-tolerated and side effects have included dizziness (2).
Toxicology studies in rats at doses equivalent to human doses of 86-89 mg/kg did not produce any toxicity (1).
For further information, please see our References Tab above.