Pterostilbene is a dietary compound often found in foods rich in antioxidants. For instance, it is abundant in grapes, cranberries, and blueberries. It is found naturally in the form of a methylated stilbene molecule. Thus, it is quite similar to resveratrol, another popular antioxidant. These two molecules have numerous similarities and benefits. They are even known to fight oxidative stress. However, pterostilbene is believed to be easier to absorb and utilize by the body, which is why it has recently caught the eye of researchers.
There is evidence on the anti-inflammatory benefits of pterostilbene, meaning it helps to lower oxidative stress and reduce production of reactive oxygen species, which often leads to many chronic illnesses. Oxidative stress is also one of the main causes of aging, which is why pterostilbene is often touted as one of the main supplements, along with nicotinamide riboside, that supports healthy aging.
While there is still a need to conduct more tests, there is preliminary evidence to suggest that pterostilbene may support memory, reduce brain fog, and increase mood. This is once again due to the fact that it prevents oxidative stress. Thus, it can help to keep the brain protected from neurological problems. Additionally, pterostilbene actively works to help boost dopamine levels, this may also promote healthy memory, learning, and overall mood.
The recommended dosage comes down to your weight and the reason you are using pterostilbene. Research shows it has different effects at different dosages. For instance, low doses are effective at combating oxidative stress.
In most studies on humans, the doses are usually between 200-700 milligrams or less. Even a small dose of 10mg may give the user some benefits, however, it seems that this molecule is most effective at doses around 200mg.
Pterostilbene Mode of Action
In various studies on animals, cells that were exposed to pterostilbene showed an increased production of antioxidants catalase and superoxide dismutase. Additionally, it has also been found to boost glutathione levels, which is a powerful antioxidant. It is linked to various benefits such as better detoxification and reduced oxidative stress in mitochondria. The mitochondria are the powerhouses of the cells and they are important in fighting age-related illnesses. Besides that, they ensure you have enough energy to perform at an optimal level.
Pterostilbene Side Effects & Toxicity
It is generally safe to consume pterostilbene. However, in very high doses, it might interfere with the normal functioning of certain medication. If you already take medication to control blood glucose and blood pressure, you might have to talk to a doctor first. He or she will help you to monitor any reactions you have to the compound. This way, it can help to determine whether your dosage might need any alterations.
However, even in high doses, the side effects of pterostilbene are non-existent. In short, this molecule has no recorded toxicity levels. Despite this, high dosage does not seem to increase the benefits of this molecule. Thus, it is important to follow the recommended doses.