Pramiracetam is a nootropic compound of the racetam family (others include Piracetam, Aniracetam, etc.), generally regarded as more potent than other racetams. It is well known as for improving memory, especially in those experiencing age-related cognitive decline. It may provide mild stimulation, focus and increase learning ability.
Average effective dosages range from 300-1200mg daily. Note: Pramiracetam is fat soluble and should be taken with food for best results.
Mode of Action
Pramiracetam works by increasing high affinity choline uptake (HACU) in the hippocampus, meaning it positively affects choline transport and synthesis of acetylcholine within the neurons.
Research shows Pramiracetam to be very well tolerated. LD50 in mice is aroung 4500mg per kilogram of body weight.
Pramiracetam is a nootropic of the racetam family, known for improving memory, learning ability and providing neuroprotection.
- Improves memory and delayed recall (ref) (ref)
- May decrease symptoms of neuro-degenerative diseases (ref)
- May partially reduce amnesic effects (reference)
- Overall cognitive enhancement via high affinity choline uptake (ref)
- May enhance spacial learning and memory (ref)
Pramiracetam is known for supporting overall cognitive function. There is strong evidence that it may improve memory and have anti-amnesic effects, especially in those suffering from age related cognitive decline. Research shows it also has the ability to improve learning ability and may also improve delayed recall.
Pramiracetam is also known for providing neuro-protection and even reversing damage from brain injuries or trauma.
Pramiracetam Studies and Side Effects
Research shows Pramiracetam is well tolerated. Human studies showed rare instance of headache as a side effect, and a single report decreased appetite and dizziness.
A significant amount of research has been conducted on Pramiracetam since it was discovered in the late 1970s. It was initially researched as a treatment for Alzheimer’s Disease, in which phase II testing showed some positive results as to its effectiveness.
The most promising research shows that Pramiracetam may greatly improve memory and recall. There are several studies that have centered around this subject and results are very positive.
As for all nootropic supplements research should be done on both the vendor and supplement itself before purchasing. Pramiracetam is available online, however, the company should always provide a third party certificate of analysis for quality and purity assurance (as does Pure Nootropics).
Also note, Pramiracetam is known to have a very bitter, unpleasant taste, so it may be preferable to purchase capsules as opposed to powder.