PQQ (Pyrroloquinoline quinone) Capsules

Product Description

PQQ (Pyrroloquinoline quinone) is a small bioactive, non-vitamin compound which acts as a REDOX (reduction-oxidation) agent and supports mitochondrial function (1).

PQQ (Pyrroloquinoline quinone) Benefits

• Supports mitochondrial function (ref)*
• Promotes cognitive function while aging (ref)*
• May improve sleep quality (ref)*
• Promotes healthy cholesterol levels (ref)*

PQQ (Pyrroloquinoline quinone) is emerging as a subject of interest in the medical community, but thus far, there has not been a large amount of research or trials conducted with humans, except for those studies referenced above.*

The following are examples of dynamics associated with PQQ (Pyrroloquinoline quinone) through the animal model and may not be representative of the effects in the human body:

• May reduce oxidative stress (in rats)(ref)*

Description

PQQ is a supplement that is not discussed very often but is critical if you want improved energy, better sleep, reduced stress and enhanced memory – due to the first three benefits. PQQ acts as a vitamin-like compound in the REDOX process within mitochondria. This process controls the amount of energy these “power supplies” are able to produce, so having more PQQ available in your body improves the amount of energy you can produce. PQQ also protects mitochondria, which it does in two main ways: by maintaining mitochondrial mass and stimulating their regeneration. Meaning not only will they perform for you better, and give you more energy in every cell in your body, but also stop them from degenerating – plugging any energy leaks your body might have already that is giving you a sense of fatigue or low energy.

Dosage

Pure Nootropics PQQ provides 20 mg per 1 capsule.  Suggested use for adults is 1 capsule by mouth daily with a meal.If you are taking any medications, always consult with you Healthcare Practitioner before beginning any new supplement.

The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• Supports mitochondrial function*
Harris, CB, et al. “Dietary Pyrroloquinoline Quinone (PQQ) Alters Indicators of Inflammation and Mitochondrial-Related Metabolism in Human Subjects.” J Nutr Biochem, vol. 24, no. 12, Dec. 2013, pp. 2076–84., doi:10.1016/j.jnutbio.2013.07.008.
• Promotes cognitive function while aging*
Itoh, Y, et al. “Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions.” Adv Exp Med Biol, vol. 876, 2016, pp. 319–325., doi:10.1007/978-1-4939-3023-4_40.
• May improve sleep quality*
Nakano, Masahiko, et al. “Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep.” Functional Foods in Health & Disease–Nakano, vol. 2, no. 8, 2012, www.ffhdj.com/index.php/ffhd/article/view/81.
• Promotes healthy cholesterol levels*
Nakano, M, et al. “Effects of Pyrroloquinoline Quinone Disodium Salt Intake on the Serum Cholesterol Levels of Healthy Japanese Adults.” J Nutri Sci Vitaminol (Tokyo), vol. 61, no. 3, 2015, pp. 233–40., doi:10.3177/jnsv.61.233.

The following are examples of dynamics associated with PQQ (Pyrroloquinoline quinone) through the animal model and may not be representative of the effects in the human body:
• May reduce oxidative stress (in rats)*
Ohwada, Kei et al. “Pyrroloquinoline Quinone (PQQ) Prevents Cognitive Deficit Caused by Oxidative Stress in Rats.” Journal of clinical biochemistry and nutrition vol. 42,1 (2008): 29-34. doi:10.3164/jcbn.2008005

1. “Pyrroloquinoline quinone”. Examine.com, published Nov 20, 2013. Last updated Oct 10, 2018. https://examine.com/supplements/pyrroloquinoline-quinone/.
2. Chowanadisai, Winyoo et al. “Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression.” The Journal of biological chemistry vol. 285,1 (2010): 142-52. doi:10.1074/jbc.M109.030130
3. Nakano, M, et al. “Acute and Subchronic Toxicity Studies of Pyrroloquinoline Quinone (PQQ) Disodium Salt (BioPQQ™) in Rats.” Regul Toxicol Pharmacol, vol. 70, no. 1, Oct. 2014, pp. 107–21., doi:10.1016/j.yrtph.2014.06.024.

Pyrroloquinoline quinone Certificate of Analysis 05/22