Studies over the past three decades have shown piracetam benefits in three major areas. First, piracetam enhances performance in learning and memory tests in the short term. Experiments have also shown piracetam to protect against neurological degradation over time, which is why it is effective for both the young and elderly. Those suffering from alcohol-related neuronal loss can see protective benefits from piracetam products as well.
Every individual reacts differently to piracetam, but the chemical composition allows the drug to enter the bloodstream rapidly and unchanged. Peak plasma concentration among fasting subjects is achieved in around 30 minutes. The half-life for the central nervous system is around 7.7 hours and 5 hours for plasma. Within 30 hours, the piracetam will have completely left the bloodstream.
Beginner piracetam use should involve around 1.5 – 6.5 grams per day ingested between 1 – 3 doses. According to some studies, the most effective dose for cognitive enhancement is 4.8 grams per day.
Mode of Action
Despite years of study, the exact cause of piracetam cognitive enhancement is still unknown. There are a series of four theories:
1. Membrane fluidity – piracetam provides higher membrane fluidity, which allows signaling molecules to cross more rapidly. This enhanced cell signaling may lead to the improved cognitive abilities.
2. Improved glutamate neurotransmission – studies have shown that piracetam (over 500mg / kg) can bind glutamate receptors for better synaptic transmission
3. Enhanced protein and phospholipid synthesis
4. Acetylcholine neurotransmission – studies indicate an increase in receptor density with piracetam use
Piracetam has a relatively high toxicity level according to all available research. Doses of 4.5g per pound provided no serious toxic effects in animal trials. In humans, doses of 8g per day resulted in few health problems while reproductive studies prove no adverse effect for pregnant women.
If you buy piracetam online from Pure Nootropics, expect arrival within the continental U.S. between 5 – 7 days.
For more information about piracetam, please visit our blog to educate yourself.
Piracetam is the first nootropic developed in the 1960s and continues to be one of the most popular cognitive enhancing drugs.
- Enhanced memory and learning capabilities (reference)
- Age related neuro / brain protection (ref)
- Protects the brain after injury (ref)
- Depression / anxiety relief (ref)
- Prescription drug for Alzheimer’s/Parkinson’s in many countries (not USA) (ref)
- Mild side effects even with extreme doses (ref)
Developed in the 1960s, piracetam is the oldest drug within the racetam family and the one that coined the term “nootropics” in the first place. Piracetam is a synthetic compound that is a derivative of GABA. Since the 1960s and 70s when it was first discovered, there have been numerous studies in favor of the drug for a variety of different reasons.
First, piracetam is primarily useful for memory formation and learning ability. Studies suggest piracetam is useful for elderly individuals who are suffering from age related memory decline (such as Alzheimer’s disease or senile dementia). Studies on humans and animals show that piracetam can improve the long and short-term memory of most participants.
One of the ways piracetam is so effective is through increased acetylcholine uptake. Essentially, the part of the brain that is used to create memories (called the hippocampus) sucks up more of this brain chemical called acetylcholine, which leads to more memories. This is often why people take a choline supplement in addition to the racetam.
Piracetam isn’t a flashy or super potent nootropic, but that means it is relatively safe and has good feedback. Research indicates that piracetam is a well-tolerated drug and the toxicity levels in humans is very high. People are taking doses of 5+ grams in some cases, though we do not recommend you start here.
Anyone who is interested in buying piracetam should look at all the evidence beforehand in order to have a clearer picture of what they are buying. There are dozens of piracetam studies that are helping people to find out more about the improvements that they can see with the risks alongside it.
Beyond the piracetam studies showing efficacy and safety, there are those that have novel applications. For example, one piracetam study showed that choline and piracetam combined was more effective than either of them alone. This suggests there is a synergy between the two compounds.
Piracetam Side Effects
Some people who take piracetam have side effects though this is a rare occurrence. It is a well-tolerated nootropic drug and few people have ever mentioned complaints about toxicity or the like. However, there are some issues that can arise as with any nootropic or supplement. Some people who take piracetam mention feeling gastrointestinal distress.
Other people who take piracetam find that they get headaches or jaw pain as a result of too little choline in their diet. This is a downstream effect of better memory and cognition, but it still can be avoided nonetheless!
Of course we are biased, but Pure Nootropics is the best place to buy piracetam and for good reason. Unlike many other vendors online, we have third party certificates of analysis and the PDF for you to read for yourself. This ensures that you get a safe product that is free from manufacturer errors.
Given that piracetam is relatively safe, it is more likely that you would get a bad batch from a vendor than you would have side effects of piracetam from the drug itself. This is why the purchasing decision can be so important.