Optimal Energy Complex combines the best of energy and focus supplements: Caffeine, L-theanine, Theobromine, Theacrine (TeaCrine®), and Dynamine™ (Methylliberine). Caffeine, L-theanine, and Theobromine work together to provide alertness that is balanced by the calming effects of L-theanine. Theacrine (TeaCrine®) is derived from Kucha tea leaves and provides focus and energy. Combining Theacrine with Dynamine™ (Methylliberine) provides exceptional wakefulness without effects on heart rate or blood pressure (1, 2).
WARNING: Optimal Energy Complex is one of the most powerful legal stimulants on the market. DO NOT take more than 1 capsule. DO NOT take if you are sensitive to caffeine or stimulants. We suggest that you take this product with food.
Optimal Energy Complex Benefits
Caffeine + L-Theanine + Theobromine Combination Benefits
- May improve cognitive performance (ref)*
- Promotes the benefits of Caffeine without unwanted effects (ref)*
- Supports focus and attention (ref)*
- Promotes wakefulness and alertness (ref)*
- L-Theanine is General Recognized As Safe (GRAS) by U.S. FDA (ref)
- A naturally occurring, mild stimulant responsible for the mood-enhancing effects of chocolate (ref)*
Theacrine (TeaCrine®) Benefits
- May enhance energy, focus, and concentration (ref)*
- Non-habit-forming source of energy (ref)*
- GRAS (Generally Recognized as Safe) (ref)*
- Combined with caffeine, supports cognitive function (ref)*
- Combine with caffeine for greater bioavailability (ref)*
- Preliminary clinical trials demonstrate it can be combined with Theacrine (Teacrine®) for exceptional results without stimulatory effects on heart rate or blood pressure elevations (ref)*
- Anecdotal evidence has likened its effects to Theacrine (TeaCrine®) and it may enhance energy, mood, and focus. Clinical, safety, and toxicology studies are taking place currently (ref)*
- GRAS (Generally Recognized as Safe) (ref)*
Optimal Energy Complex Mode of Action
Optimal Energy Complex focuses on methylxanthines (a class of stimulatory compounds), alkaloid compounds which are similar in structure to methylxanthines, and the amino acid found in green tea, L-Theanine. Caffeine, Theobromine, and L-Theanine can all be found naturally occurring together in some teas (3).
Methylxanthines include Caffeine and Theobromine and are found together in cocoa, cacao, and chocolate (3).
Caffeine is a stimulant found in coffee, tea, chocolate, guarana, yerba mate, and the kola nut. It is an adenosine receptor antagonist, meaning that it prevents adenosine from being active. Adenosine is one of the neurotransmitters responsible for drowsiness, and caffeine provides wakefulness through this mechanism of blocking adenosine (4).
Caffeine also interacts with the serotonergic system and can cause changes in the acetylcholine and dopamine systems within the body (4). Caffeine does produce side effects, such as large amounts acutely raising blood pressure. Mild side effects can include anxiety, agitation, restlessness, fidgeting, irritability, elevated or irregular heart rate, and others (5).
Theobromine is a mood-enhancing compound naturally present in chocolate. Theobromine is a mild stimulant that interacts with the dopamine pathways in the brain (6). Theobromine stimulates the central nervous system by blocking adenosine receptors (7).
The combination of caffeine and theobromine in chocolate, cocoa, and cacao is linked to the pleasurable effects and appeal of chocolate. Theobromine has also shown promise in promoting blood vessel health (8).
Alkaloids similar to methylxanthines
Theacrine and Dynamine™ (Methylliberine) are similar to methylxanthines, but they are structurally different.
Theacrine occurs in Kucha tea leaves and is very similar to a caffeine molecule (1). Theobromine and caffeine in certain plants will convert into Theacrine (9). Theacrine causes signaling changes on the adenosine receptors in the brain, like caffeine, and can also influence the dopaminergic signaling pathways like caffeine. However, unlike caffeine, Theacrine is non-habit forming and does not change the heart rate or blood pressure (1). When combined with caffeine, bioavailability is enhanced (10).
Dynamine™ (Methylliberine) is an isomer of Theacrine, and it can be found in kucha tea and some species of coffea. It is a byproduct of metabolic reactions between the methylxanthines and methyluric acid. The plants accumulate caffeine and begin transforming theobromine to caffeine. The caffeine and theobromine are converted to Theacrine, and Theacrine replaces all of the caffeine. Theacrine will then be reduced, as levels of liberine rise, and its precursor methylliberine is present (9).
Dynamine™ (Methylliberine) provides the effects of Theacrine without any changes in heart rate or blood pressure elevations, and the combination of the two has demonstrated that they are synergistic (2).
L-Theanine is an amino acid which naturally occurs in tea leaves and some forms of mushrooms.
Tea (Camellia sinensis) contains 1-3% of L-theanine. It is used in a supplemental form isolated directly from tea leaves or prepared via chemical synthesis or biosynthesis (11). Green, black, oolong, and white tea all contain L-Theanine in varying amounts (12). Green tea and black tea contain the highest amounts of L-theanine, but the studies are conflicted about which of the two has the most (13).
Combined with caffeine, L-Theanine may improve performance on cognitively demanding tasks through its synergistic effects. L-Theanine may help control blood pressure and may lessen some of the unwanted effects of caffeine (14).
Optimal Energy Complex Dosage
Pure Nootropics’ Optimal Energy Complex provides 100 mg of Caffeine, 200 mg of L-Theanine, 125 mg of Theacrine (TeaCrine®), 125 mg of Dynamine™ (Methylliberine), and 150 mg of Theobromine per 1 capsule. Suggested use for adults is 1 capsule by mouth once daily.
Dynamine™ is a trademark and TeaCrine® is a registered trademark and protected by Patents Pending, Serial No. 61/903,362; under exclusive global distribution by Compound Solutions, Inc.
Optimal Energy Complex Side Effects and Toxicity
Caffeine Side Effects
In moderate doses, caffeine is usually well-tolerated in adults and children. Side effects may include insomnia, restlessness, nervousness, nausea, vomiting, gastric irritation, tachycardia, tremors, quickened respiration, convulsions, headache, agitation, anxiety, chest pain, and irregular heartbeat. Large doses of caffeine may cause tachycardia, metabolic acidosis, ketosis, and hyperglycemia. Children and the elderly may experience more adverse effects from caffeine. Chronic use of large amounts of caffeine may cause tolerance, psychological dependence, and abrupt stopping of caffeine use may cause physical withdrawal symptoms (15).
The lethal dose of caffeine in adults is approximately 10-14 grams per kilogram, but fatality has also occurred at lower doses (15).
Caffeine has many pharmaceutical medication and herb interactions. If you are taking any medications, herbs, or supplements, please consult your healthcare practitioner before beginning a supplementation with caffeine.
One of the major interactions we note is between ephedrine and caffeine, which may cause high blood pressure, stroke, myocardial infarction, seizures, and death (15). If you are taking any medications, herbs, or supplements, please consult your healthcare practitioner before beginning supplementation with caffeine.
L-Theanine Side Effects
L-Theanine, regardless of chemical synthesis, biosynthesis, or naturally occurring, is General Recognized As Safe (GRAS) by U.S. FDA.
L-Theanine is very well tolerated, and side effects may include headaches and increased sleepiness (11).
Animal research indicates that the No Observed Adverse Effect Level of L-theanine is greater than
4000 mg/kg in rats (11).
(Note: Due to L-Theanine’s effects on reducing blood pressure, please see the list of possible interactions with pharmaceutical blood pressure medications and herbs/supplements that may occur below.)
Regarding interactions with other medications/herbs/supplements: If you are taking blood pressure medications (antihypertensive medications) to lower blood pressure, be moderately cautious combining those medications with L-Theanine, as evidence in animal research has noted that L-Theanine may lower high blood pressure. Using L-Theanine and antihypertensive medications may lower blood pressure too much. Some of these medications include Vasotec (enalapril), Capoten (captopril), Cozaar (losartan), Diovan (valsartan), Norvasc (amlodipine), Cardizem (diltiazem), HydroDiuril (hydrochlorothiazide), Lasix (furosemide), and others). Please consult with your healthcare practitioner if you are on any blood pressure medications prior to beginning supplementation with L-Theanine (11).
Using Herbs and supplements that lower blood pressure should also be avoided when taking L-Theanine due to the same mechanism of L-Theanine on blood pressure that applies to pharmaceutical medications. Some of these herbs and supplements include casein peptides, cat’s claw, Andrographis, coenzyme Q10, L-arginine, fish oil, lyceum, stinging nettle, and others (11).
If you are taking any stimulant medications, using L-Theanine and the stimulants together may decrease the effectiveness of the prescribed stimulants, some of which include epinephrine, Tenuate (diethylpropion), Lonamin (phentermine), Sudafed (pseudoephedrine), and others (11).
Theobromine Side Effects
Theobromine is toxic to many animals, but in normal consumption, it is safe for humans. A standard 40 g dark chocolate bar contains about 250 mg of Theobromine (8). Chocolates with higher cocoa/cacao content have more theobromine than milk chocolate.
Higher doses of 50-100 g of cocoa caused sweating, severe headaches, and trembling (16).
Theobromine is very toxic to dogs because they metabolize it so slowly, and they can experience theobromine poisoning (17). Please keep Optimal Energy Complex out of the reach of curious pets.
Theacrine (TeaCrine®) Side Effects
Theacrine (TeaCrine®) is considered GRAS by the U.S. FDA (Generally Recognized As Safe).
The lethal dose for mice was achieved at 810.6 mg/kg, which equates to 4 g per a 76 kg human (18).
Dynamine™ Capsules Side Effects
Toxicology studies are currently taking place for Dynamine™. It is believed to be similar to Theacrine (TeaCrine®) in that it does not affect blood pressure and heart rate like caffeine can.
For more information, please see our references tab.