Mucuna L-Dopa 15% Benefits
When people are under psychological stress, they experience an increase in blood cortisol levels. This stress hormone is meant to help the body deal with the long-term effects of stress. Excess cortisol affects blood pressure, suppresses the immune system, contributes to obesity and decreases the libido. Mucuna (L-Dopa) may reduce blood cortisol levels, leading to improvement in the symptoms of stress and increased overall subjective well-being.
One long-standing use of herbal remedies is their effect on the human libido, and Mucuna pruriens is no exception. We now know that, in this case, it is due to the role that dopamine plays in the brain’s reward pathway. This pathway is involved in providing a pleasurable incentive for the pursuit of survival behaviors, such as eating and sex.
Mucuna L-Dopa 15% Dosage
This supplement is standardized to 15% L-Dopa, therefore 500 – 1000mg of Mucuna Pruriens extract per day is a generally effective dose. As a natural source of the dopamine precursor, Mucuna pruriens is more effective than manufactured supplements because it also has co-factors that improve L-DOPA bioactivity.
Mucuna L-Dopa 15% Mode of Action
The bioactive ingredient in Mucuna pruriens that is behind its medicinal usefulness is L-DOPA, a precursor to multiple biochemicals. It is typically present in the pods at levels of about 3-6%, although those levels are sometimes as high as 12%. The advantage of taking L-DOPA as a Mucuna pruriens derivative, instead of an isolated chemical, is that there are other chemicals in the pod that increase its absorption and effectiveness.
L-DOPA is useful in the body for synthesizing several neurotransmitters known as catecholamines. This class of amino acids includes epinephrine, norepinephrine, and dopamine.
Wherever found in the body, dopamine acts as a chemical messenger. In the body, it is involved in vasodilation, immune response, and a wide variety of gastrointestinal regulation. In the central nervous system (CNS), however, it works as a neurotransmitter. There are several brain pathways that use dopamine to regulate essential functions. These pathways are involved in intrinsic rewards, motor control, and hormone release.
Pure L-DOPA converts to dopamine in the peripheral nervous system (PNS) just like it does in the brain and spinal cord. Excess dopamine in the PNS is behind most of the negative side effects seen with pure L-DOPA. For this reason, medical practitioners often give a second chemical like carbidopa, which can counter that excess, along with it. Mucuna pruriens causes fewer side effects than pure L-DOPA because it has carbidopa in it.
Mucuna L-Dopa 15% Side Effects & Toxicity
Most commonly, side effects associated with this supplement include signs of gastrointestinal distress, such as nausea and abdominal bloating. Rarely, people may suffer vomiting and insomnia. At larger doses, this supplement might cause headaches, confusion, pounding heartbeat, and agitation. First pass effect data is not available for this supplement.
Mucuna L-Dopa 15% Research
Ayurvedic medicine recognizes this herbal supplement’s ability to purify the body and counteract the inflammation of arthritis. It also involves the use of Mucuna pruriens to treat pain, purify the blood, fight parasites, and remedy poisoning. However, these treatments need more research before Western medicine will embrace them as effective disease therapy.
Additionally, prolactin is a hormone that regulates the immune system, regulates cell cycles, and is involved in the production of blood. Excess prolactin in the blood, or hyperprolactinemia, can cause pituitary gland tumors, leading to visual impairment, headaches, and erectile dysfunction. Bromocriptine is a dopamine agonist long used to treat this condition. Hormone agonists sensitize receptors, so they bind the hormone more readily. Increasing the amount of available hormone has the same effect, which is the basis for research investigating Mucuna pruriens as a treatment for hyperprolactinemia.