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Fasoracetam Capsules
$23.99
- Fasoracetam (N-(5-Oxo-D-prolyl)piperidine) (ref)* and its mechanism of action is not fully understood at this time.
The pre-clinical animal studies, which may not be representative of the effects in humans, indicate that Fasoracetam modulates and activates the metabotropic glutamate receptors (mGluR) (2)*. Pre-clinical animal studies demonstrate Fasoracetam’s ability to increase acetylcholine release, uptake, and GABAb (3)*.
- Since its development in the 1990s in Japan, Fasoracetam studies and human clinical trials have been underway and have demonstrated its safety profile is well tolerated (2)*.
- Assured Purity: Rigorously tested for quality & purity by third-party Certificate of Analysis*
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Fasoracetam is a nootropic compound in the racetams group.
- Fasoracetam (N-(5-Oxo-D-prolyl)piperidine) (ref)* and its mechanism of action is not fully understood at this time.
The pre-clinical animal studies, which may not be representative of the effects in humans, indicate that Fasoracetam modulates and activates the metabotropic glutamate receptors (mGluR) (2)*. Pre-clinical animal studies demonstrate Fasoracetam’s ability to increase acetylcholine release, uptake, and GABAb (3).*
- Since its development in the 1990s in Japan, Fasoracetam studies and human clinical trials have been underway and have demonstrated its safety profile is well tolerated (2)*.
- Assured Purity: Rigorously tested for quality & purity by third-party Certificate of Analysis*
Fasoracetam Chemical Properties
- Molecular formula: C10H16N2O2
- Molar mass: 25 g/mol
- CAS number: 110958-19-5 (1)
- Also known as: NS-105 (1)
- Bioavailability in humans*: Peak plasma level in young adults approximately 1.3 hours, and approximately 2.1 hours in elderly (4)
- Bioavailability in the animal model: Peak plasma level within 1 hour (4)(5)
- Systemic bioavailability in the animal model: 90% in dogs, 79% in monkeys, and 97% in rats (5)
- Elimination in the animal model: approximately 90% excreted in urine for rats and monkeys, 60% excreted in dogs (5)
- Half-Life Data in the animal model: 3 hours for monkeys, 2.1 hours for dogs, 0.67 hours for rats (5)
Fasoracetam Capsules
Pure Nootropics’ offers Fasoracetam in 20 mg capsules.
Fasoracetam Toxicity
In clinical trials, Fasoracetam was well tolerated (6)(2), but care is needed when administering to elderly individuals because of the potential for elderly renal (kidney) impairment which may inhibit timely elimination of the compound. This may cause elevated plasma concentration levels of the compound because the kidneys are not able to quickly filter the compound due to age-associated kidney changes. Please consult your healthcare practitioner before taking Fasoracetam, especially if there are any kidney impairments (4).
For further information, please see our References Tab above.
Additional Information
| Weight | 0.11875 lbs |
|---|---|
| Dimensions | 1.95 × 1.95 × 3.95 in |
| Quantity: | 60 x 20mg, 180 x 20mg |
5 reviews for Fasoracetam Capsules
The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition<strong. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.
1. “Fasoracetam.” PubChem Open Chemistry Database, pubchem.ncbi.nlm.nih.gov/compound/198695#section=Top.
2. Moskowitz, D. H., Dr. Finding the Genetic Cause…A Journey into the Precision Medicine that Could Affect Millions Worldwide. 30 Jan 2017, BookBaby. ISBN: 1483590984, 9781483590981.
3. Elia, Josephine et al. “Fasoracetam….and…glutamatergic gene network variants disrupting mGluR neurotransmitter signaling” Nature communications vol. 9,1 4. 16 Jan. 2018, doi:10.1038/s41467-017-02244-2.
4. Kumagai Y, Yokota S, Isawa S, Murasaki M, Mukai H, Miyatake S. Comparison of pharmacokinetics of NS-105…in elderly and young subjects. Int J Clin Pharmacol Res. 1999;19(1) 1-8. PMID: 10450537. http://europepmc.org/abstract/med/10450537.
5. Mukai, Hideya et al. Pharmacokinetics of NS-105, a Novel Cognition Enhancer, Arzneimittelforschung. 1999. 49 (11), pp. 881-890. DO – 10.1055/s-0031-1300521. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0031-1300521.
6. Findling, Robert, and Helen R. Stulman. “Transforming…Paradigms….” Aevi Genomic Medicine, 29AD, aevigenomicmedicine.gcs-web.com/static-files/550762a8-6d9f-4cd6-933f-5ff7e8e12ab8.
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Austin (verified owner) –
I’ve been trying nootropics for a while now and I don’t know whether it’s this or the magnesium product but within two days I’ve felt awesome a couple of times now, big big :-). Also tried adrafinil once so far with apparent effect which I did not have with a similar product.
Matt (verified owner) –
Fasoracetam is fantastic. By reducing anxiety, it quiets and focuses the mind. My only complaint, and it is a significant one, is that my credit card number was stolen after the purchase and it was likely compromised on the website because I can’t think of anywhere else it could have happened. To be clear, I do not have proof it was compromised here, so I apologize if I am wrong, but it seems very likely given my spending habits. I recommend using a secure form of payment, such as a prepaid credit card if you are going to make a purchase from this website. The product was great, but online purchases can be risky.
Eric Ballaster –
Hi Matt, very sorry to hear this has happened to you. I’ve spoken to our IT department and we have not had any recent hacking violations. Additionally when credit cards are stored on our site, we are only able to see the last 4 digits of the card number on both the back end of purenootropics.net site and through our merchant processor. Further, we do have SSL encryption established to prevent any issues such as these and therefore we are quite confident our information was not compromised through our website.
Please let us know if you have any further questions or concerns. We take this issues very seriously and want you to always feel safe ordering through Pure Nootropics.
We appreciate your business.
Chandler Christensen (verified owner) –
Fantastic product. Got me feeling focused and clear headed within 30 minutes. But on top of that, free 2 day shipping! Pure nootropics is the way to go. Great product, great service!
Harris (verified owner) –
Did not notice much of an effect with this, if any at all.
Richard Harrell (verified owner) –
Love this product but when will it return? Out of stock a couple days now!!