EGCG (epigallocatechin-3-gallate) is a catechin polyphenol extracted from green tea leaves (Camellia Sinensis) (1).
EGCG 50% Green Tea Extract Capsules Benefits
- Promotes antioxidant activity (ref)*
- Supports mood (ref)*
- Promotes fat reduction (ref)(ref)*
- May improve cognitive function (when paired with L-Theanine) (ref)*
- Supports cardiovascular health (ref)*
EGCG 50% Green Tea Extract Capsules Mode of Action
The health benefits of green tea consumption are widely known. The specific extract of one of green tea’s catechins, EGCG, has emerged as a supplemental, targeted method of delivery in the modern era.
A catechin is a type of flavanol contained in the leaves of green tea. Approximately 30% of the dry weight of the leaves are favonols or flavonols. The catechins are constituents of the flavonols. Green tea contains four types of catechins including EGCG (epigallocatechin-3-gallate), EGC (epi-gallocatechin), ECG (epicatechin gallate), and EC (epicatechin)(1).
EGCG is the most abundant catechin in green tea (2) as well as the most potent (1). The catechins vary in chemical structure and differing amounts of gallic acids (1).
Animal research suggests that EGCG reduces the oxidants caused by ROS (reactive oxygen species) which are byproducts of oxidation. Studies in mice demonstrated that long term administration increased levels of BDNF (brain-derived neurotrophic factor) and enhanced the memory of aged mice (3).
EGCG has also demonstrated the ability to promote fat reduction when paired with exercise (4). EGCG is helpful in maintaining cardiovascular and metabolic health (2).
EGCG 50% Green Tea Extract Capsules Dosage
Pure Nootropics’ EGCG 50% Green Tea Extract Capsules provide 250 mg of a standardized 50% extract from 500 mg dry weight of Camellia sinensis dried leaves per 1 capsule. Suggested use for adults is 1 capsule by mouth daily, or as directed by your healthcare practitioner.
EGCG 50% Green Tea Extract Capsules Side Effects and Toxicity
EGCG supplements are safe in doses of 800-1600 mg; however, the higher doses are associated with more nausea than doses of 400-800 mg (1).
In dogs, toxicity was achieved at excessive doses greater than 500 mg/kg, and doses of 2000mg/kg in rats lead to hemorrhagic lesions in the stomach and intestines resulting in lethality (1).
Although EGCG side effects include gastrointestinal symptoms, nausea associated with taking supplements is not inherently linked to stomach damage at the dosages normally consumed (1).
For further information, please see our References Tab above.