DHM (Dihydromyricetin) Capsules

Product Description

DHM (Dihydromyricetin), also known as Ampelopsin and Ampelopsin grossedentata, is a flavonoid of the Japanese Raisin Tree, Hovenia dulcis (3).  DHM may assist the body in alcohol metabolism.

DHM Dihydromyricetin Capsules Benefits

• May decrease acetaldehyde (the toxic metabolite of alcohol) in humans (ref)*

DHM is emerging as a subject of interest in the medical community, but thus far, there has not been a large amount of research or trials conducted with humans, except for those studies referenced above.*

 The following are examples of dynamics associated with DHM through the animal model:

• May lessen the effects of alcohol consumption (in rats) (ref)*
• May improve lipid metabolism (ref)*
• May reduce oxidative stress on the liver after alcohol consumption (in mice) (ref)*

Description

We’re sure you love to enjoy yourselves on occasion as much as we do… and we’re also sure you hate the next day effects that alcohol can have, especially on your brain and performance levels.

How does this happen?

And more importantly, can we stop it?

To answer the first question we must answer the second.

In short, when we drink more alcohol than our livers can safely process (which is around 1 unit per hour, in other words nothing close to a party), the amount of alcohol in our blood builds up and causes a backlog waiting to be processed.

Once the liver gets round to it, it produces toxic compounds which linger in our bodies and cause the dreaded feelings we experience the next day – sluggishness, uneasiness, and fast-beating hearts.

This happens because our livers only contain a certain amount of the enzymes necessary to break down alcohol and the toxic compounds it produces.

Which is where DHM comes in. DHM increases the amounts of these enzymes in the liver, meaning we stress our body for less time when we drink, and also ensuring our symptoms the next day are bearable or non-existent.

This product is a must if you’re looking to maximize your performance long term, or if you’re simply getting older and wondering how you can have that after work beverage without sacrificing your next morning for it.

Dosage

Pure Nootropics’ DHM Dihydromyricetin provides 300 mg per 1 capsule.  Suggested use for adults is 1 capsule by mouth prior to bed and 1 capsule in the morning after consuming alcohol, or as directed by your healthcare practitioner.

The references below are not meant to imply that any of our products treat, cure, or diagnose any disease or human condition. References to clinical studies and pre-clinical studies may use varying dosages and may not represent the dosages or subsequent results of products we sell; however, the references provided are pertinent to the subject supplement itself. References provided are intended for research and informational purposes only and do not represent the entire body of knowledge available on the subject(s) referenced; nor do they represent all possible outcomes associated with the subject(s) referenced including, but not limited to, adverse effects, precautions, or chemical interactions within the human body. The Content provided on this website is not intended to be a replacement for professional medical advice, treatment or diagnosis. Never ignore the advice of a medical professional or delay in attaining professional advice because of information or impressions you gather on this website. Choosing to rely on any information provided by the Content of this website is solely at your own risk. We encourage our audience to do their own research beyond the resources we have provided so your decision is as educated as possible.

• May decrease acetaldehyde (the toxic metabolite of alcohol) in humans*
Okuma, Yutaka, et al. “Effect of Extracts from Hovenia Dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol.” Nippon Eiyo Shokuryo Gakkaishi, vol. 48, no. 3, 1995, pp. 167–172., doi: https://doi.org/10.4327/jsnfs.48.167.
• May improve lipid metabolism*
Silva J, Yu X, Moradian R, Folk C, Spatz MH, Kim P, Bhatti AA, Davies DL, Liang J. Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism. Alcohol Clin Exp Res. 2020 May;44(5):1046-1060. doi: 10.1111/acer.14326. Epub 2020 Apr 8. PMID: 32267550; PMCID: PMC7211127.”
• May lessen the effects of alcohol consumption (in rats)*
Shen, Yi et al. “Dihydromyricetin as a novel anti-alcohol intoxication medication.” The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 32,1 (2012): 390-401. doi:10.1523/JNEUROSCI.4639-11.2012
• May reduce oxidative stress on liver after alcohol consumption (in mice)*
Wang, Mingchun, et al. “Preliminary Characterization, Antioxidant Activity in Vitro and Hepatoprotective Effect on Acute Alcohol-Induced Liver Injury in Mice of Polysaccharides from the Peduncles of Hovenia Dulcis.” Food and Chemical Toxicology, vol. 50, no. 9, Sept. 2012, pp. 2964–2970., doi.org/10.1016/j.fct.2012.06.034.

1. “Alcohol Metabolism: An Update.” National Institute on Alcohol Abuse and Alcoholism, vol. 72, July 2007, pubs.niaaa.nih.gov/publications/aa72/aa72.htm.
2. Okuma, Yutaka, et al. “Effect of Extracts from Hovenia Dulcis Thunb. on Alcohol Concentration in Rats and Men Administered Alcohol.” Nippon Eiyo Shokuryo Gakkaishi, vol. 48, no. 3, 1995, pp. 167–172., doi: https://doi.org/10.4327/jsnfs.48.167.
3. “Hovenia dulcis”. Examine.com, Published Jul 12, 2013. Last updated Oct 10, 2018. https://examine.com/supplements/hovenia-dulcis/#ref10.
4. Shen, Yi et al. “Dihydromyricetin as a novel anti-alcohol intoxication medication.” The Journal of neuroscience : the official journal of the Society for Neuroscience vol. 32,1 (2012): 390-401. doi:10.1523/JNEUROSCI.4639-11.2012
5. Wang, Mingchun, et al. “Preliminary Characterization, Antioxidant Activity in Vitro and Hepatoprotective Effect on Acute Alcohol-Induced Liver Injury in Mice of Polysaccharides from the Peduncles of Hovenia Dulcis.” Food and Chemical Toxicology, vol. 50, no. 9, Sept. 2012, pp. 2964–2970., doi.org/10.1016/j.fct.2012.06.034.
6. “Dihydromyricetin Safety Data Sheet.” Cayman Chemicals, www.caymanchem.com/msdss/23549m.pdf.
7. Hongliang, Li, et al. “The Versatile Effects of Dihydromyricetin in Health,” Evidence-Based Complementary & Alternative Medicine. 2017,
doi: 10.1155/2017/1053617

Dihydromyricetin Certificate of Analysis 05/2020