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Bacopa Monnieri is a popular adaptogen used in Ayurvedic traditional medicine, known as “Brahmi”, which has now been expertly formulated into an exact fingerprint of its bioactive constituents (called Serotonin-Active Bacopa Glycosides, or SABG).
Pure Nootropics has chosen this high-quality, standardized extract form of Bacopa Monnieri called Bacognize® (2, 1).
Bacognize® Bacopa Monnieri Benefits
- Promotes improved cognitive processing (ref)*
- Supports mood and well-being (ref)*
- Promotes improved memory (ref)*
- Supports focus and attention (ref)*
Bacognize® Bacopa Monnieri Mode of Action
Bacognize® has been clinically tested in humans and has strong scientific evidence to support its benefits (1).
The unique formulation of Bacognize® enables the Bacopa extract to be active at the serotonin receptors in the brain (1) and may increase serotonin levels (2).
Bacopa Monnieri’s active chemical compounds are bacosides and bacogenins. Bacosides A and B enhance the transmission of impulses between neural synapses. Bacosides can also protect and repair neurons (2).
Most of Bacopa extract’s effects in the body are cognitive. The neurotransmitter acetylcholine is found in large amounts in the hippocampus, the part of the brain responsible for learning and memory. Maintaining acetylcholine in the brain is an integral part of cognitive health. Bacopa Monnieri extract suppresses an enzyme that breaks down acetylcholine, called acetylcholinesterase (or AChE), in the cerebral cortex. Since the enzyme responsible for breaking down acetylcholine is reduced, the amount of available acetylcholine remains higher and cognitive health is improved (3).
Together, these mechanisms provide the brain with improved conditions that improve memory, attention, focus, mood and cognitive processing from supplementation with Bacognize® (1).
Bacognize® Bacopa Monnieri Capsules
Pure Nootropics’ Bacopa Monnieri Capsules provide 300 mg of (standardized to 12% SABG) Bacognize® extract. Suggested use for adults is 1 capsule by mouth daily, or as directed by your healthcare practitioner.
Bacognize® Bacopa Monnieri Side Effects and Toxicity
Bacopa is well tolerated but may cause mild gastrointestinal side effects, such as nausea, abdominal cramps, and increased stool frequency (5, 4). Other side effects may include dry mouth, fatigue, drowsiness, and rarely, heart palpitations (5).
Bacopa extract has been studied in humans and is considered possibly safe when used orally and appropriately. The LD50 in rats of an alcohol extract of Bacopa was 17g/kg, which is a dose many, many times higher than humans consume (4).
There is not a large body of research with Bacopa and any interactions it might have with pharmaceutical medications, herbs or supplements. If you are taking any medications, please consult with your healthcare practitioner before beginning supplementation with Bacopa. Do not use if pregnant or nursing (5).