Adrafinil is a precursor to modafinil, the body converts the adrafinil to modafinil; Adrafinil and modafinil are often discussed together for this reason. Adrafinil is a mild stimulant designed to fight off sleepiness and fatigue. Adrafinil is banned by the world doping association.
Adrafinil is metabolized in the liver and has been shown to increase liver enzymes, it is often taken with milk thistle to counteract this effect. Adrafinil should not be taken by anyone with liver problems or concerns. Additionally, women taking an oral contraceptive may want to avoid adrafinil, as it can reduce the efficacy of some types of contraceptives. Adrafinil can raise blood pressure and should not be used by anyone with heart problems.
Adrafinil should be taken in 300 mg per day doses. The drug is less strong than modafinil and thus must be used in higher doses. With a lower dose, you will feel less stimulation, but it is useful when first starting out. Over time you can increase your dosage of adrafinil for the optimal effects specific to you.
Mechanism of Action
The main mechanism of action for adrafinil is as a prodrug for modafinil. Taking adrafinil gets converted in the liver into modafinil, which has the main psychoactive effects on the brain. Specifically, R-modafinil is the cause of the stimulation and enhanced concentration that often comes from using the drug. Modafinil causes downstream effects, such as increasing dopamine and adrenaline, which have an impact on your concentration and focus (among other things).
If you buy adrafinil online from Pure Nootropics, expect arrival in the continental U.S. between 5 – 7 days.
Adrafinil is a prodrug for Modafinil, which is a powerful wakefulness agent that improves concentration, focus, and alertness.
- Adrafinil is converted into Modafinil in the body to keep you alert and focused (ref)
- Adrafinil is a powerful wakefulness agent without amphetamine-like effects (ref)
- Use of Adrafinil in high doses (animal studies) proved the safety and efficacy of the drug (ref)
Adrafinil Studies and Benefits
Many of the studies that include adrafinil are related to military performance when it really matters and times are stressful. The main benefit of adrafinil is as a prodrug for modafinil, which is far more well-researched and understood. There are numerous studies showing how adrafinil can help to improve cognition, memory and reduce fatigue in a way that is similar to amphetamine based drugs like Adderall.
One study showed that the drug could help reduce cognitive decline and enhance performance in a cohort of military personnel who had 64 hours of work without any sleep. In these sleep deprived states, it is obvious that adrafinil is as effective as some of the most prescribed drugs.
The studies also show that adrafinil (once converted to modafinil) is without the same euphoria and addiction potential that comes with a drug like Adderall. This is obviously a whole lot safer than using these kind of amphetamine based drugs.
Adrafinil Side Effects
Of course, one of the main side effects of adrafinil is that it must be converted into modafinil in the liver. Although numerous individuals have done anecdotal research on the liver effects of adrafinil, there is some scientific evidence to suggest it can be detrimental. The liver enzymes get altered as a result of using the adrafinil. Others claim that this can be removed through the use of milk thistle, but that will be a personal test you must conduct.
Other side effects are rare, but some people complain of anxiety, irritability, and changes to mood. People often become more focused on their work, which can come across as reserved or moody even though it is not. Just keep this in mind if you are planning to use adrafinil and try not to use it daily. There are tolerance issues that you’ll want to avoid to maintain the efficacy of the drug.
There are not many adrafinil retailers online anymore because most are just taking modafinil. If you are in the market for a legal version of this prescription drug, adrafinil is a good option. At Pure Nootropics we have prided ourselves in building a reputation on high quality nootropic drugs. We have an adrafinil product that meets these standards and gives you peace of mind when improving your concentration, focus, and attention.