Adrafinil is a precursor to modafinil, the body converts the adrafinil to modafinil; Adrafinil and modafinil are often discussed together for this reason. Adrafinil is a mild stimulant designed to fight off sleepiness and fatigue. Adrafinil is banned by the world doping association.
Adrafinil is metabolized in the liver and has been shown to increase liver enzymes, it is often taken with milk thistle to counteract this effect. Adrafinil should not be taken by anyone with liver problems or concerns. Additionally, women taking an oral contraceptive may want to avoid adrafinil, as it can reduce the efficacy of some types of contraceptives. Adrafinil can raise blood pressure and should not be used by anyone with heart problems.
Adrafinil should be taken in 300 mg per day doses. The drug is less strong than modafinil and thus must be used in higher doses. With a lower dose, you will feel less stimulation, but it is useful when first starting out. Over time you can increase your dosage of adrafinil for the optimal effects specific to you.
Mechanism of Action
The main mechanism of action for adrafinil is as a prodrug for modafinil. Taking adrafinil gets converted in the liver into modafinil, which has the main psychoactive effects on the brain. Specifically, R-modafinil is the cause of the stimulation and enhanced concentration that often comes from using the drug. Modafinil causes downstream effects, such as increasing dopamine and adrenaline, which have an impact on your concentration and focus (among other things).
If you buy adrafinil online from Pure Nootropics, expect arrival in the continental U.S. between 5 – 7 days.