The first piracetam studies helped treat motion sickness in the 1960s. It wasn’t until 1971 that piracetam was studied for memory/learning enhancement and neuro protection. Researchers performed dozens of studies on animals and humans.
Quick Piracetam Findings:
- Studies show enhanced memory and learning (reference)
- Age related neuro protection (ref)
- Protects the brain after injury (ref)
- Depression / anxiety relief (ref)
- Mild side effects even with extreme doses (ref)
- Minimal risk of toxicity (ref)
In the 1960s piracetam was used in order to treat motion sickness in patients and test subjects, but in 1970s scientists discovered the cognitive effects of the drug. The piracetam studies that followed over the next 40 years have helped to shape the landscape of cognitive enhancement and even the term “nootropic” has come from the synthesis of piracetam.
Research has shown a clear link between piracetam and memory formation as well as numerous other benefits and potential side effects.
Piracetam and Memory Enhancement
Some of the most profound research is on the topic of memory enhancement and learning ability. There are many piracetam studies and Alzheimer’s disease research that show elderly individuals can benefit greatly from the smart drug. Not only will it halt age related neurological decline, but it can also provide a reversal in some instances.
This is the main reason why so many younger people are taking piracetam in order to achieve more in their education or while they are at a high performance professional job. There is plenty of evidence to suggest that piracetam is not only helpful for Alzheimer’s and memory loss patients, but also for the average middle-aged person.
Mood and Depression
When a nootropic modulates certain regions of the brain, it will alter bio chemicals that can effect memory and other aspects as well. Piracetam specifically can alter your mood in a positive way, but there are some people that have other experiences. The causes of piracetam depression are unknown, but they are rare and in most cases people actually cure their depression and anxiety with piracetam.
There are some experiences that show long term piracetam depression can be an issue, but most of the studies show that it is a mood enhancer depending on the person. Of course, this all depends on your personal biochemistry and the other ingredients you use along with piracetam.
Dosage Recommendations and Half Life
Compared to other racetams, piracetam is not all that potent and bioavailable. Because it takes many minutes to be absorbed into the body, it will last longer in your system than some of the other racetams like aniracetam or oxiracetam. The piracetam half life for plasma blood levels is much longer and thus the doses don’t need to come as often.
That being said, the piracetam dosage recommendations are quite high. Some people suggest taking 1.6 – 3.6 grams per day. There are even stories of taking 4.8 grams in order to get the full effects from piracetam. Even Reddit and Longecity (communities focusing on nootropics) show that the higher doses are most effective.
Dangers and Interactions
Studies show that piracetam can interact with other psychoactive chemicals. For instance, there are some piracetam dangers and MDMA when the two are combined. Some people experience some loss of control because the two psychoactive compounds have properties that overlap and make it overwhelming. Alcohol is another substance people discuss, but usually it is in a positive light when combining the two.